Essays about: "Dendritic cells"

Showing result 1 - 5 of 24 essays containing the words Dendritic cells.

1. 1. Role of androgen receptor signaling in the activation and differentiation of plasmacytoid dendritic cells

   University essay from Göteborgs universitet / Institutionen för biologi och miljövetenskap

   Author : Faiza Tahsin Rashid; [2023-06-27]
   Keywords : ;

   Abstract : Androgens are steroid hormones essential for the development and maintenance of male reproductive organs and secondary sexual characteristics. Plasmacytoid dendritic cells (pDCs) are immune cells that act as the first line of defense against viral infections. READ MORE

3. 2. Genetic manipulation to improve efficacy of dendric cell adoptive immunotherapy against cancer in dogs

   University essay from Karlstads universitet

   Author : Felicia Berglund; [2023]
   Keywords : Adoptive immunotherapi;

   Abstract : To improve the efficacy of the dendritic cell vaccine Alv B DC from Alv B, the PD-L1 expression in cancer cells was attempted to be reduced through a transfection with a custom designed siRNA. Before transfecting the dendritic cells, the siRNA functionality had to be tested through flow cytometry, that resulted in negative results and therefore led to a RT-qPCR protocol that indicated that the siRNA was functional. READ MORE

4. 3. Investigating the crosstalk between estrogen receptor beta in colorectal cancer and tumor-associated macrophages

   University essay from KTH/Proteinvetenskap

   Author : Alicia Bodin; [2023]
   Keywords : estrogen; macrophages; colorectal cancer; qPCR; cell culture; östrogen; makrofager; tjocktarmscancer; qPCR; cellodling;

   Abstract : Tjock-och ändtarmscancer (kolorektalcancer) är den tredje vanligaste cancertypen och den näst vanligaste cancer-relaterade dödsorsaken i världen. Östrogen har visat sig ha en skyddande roll mot kolorektalcancer och östrogenreceptor beta är den dominerande östrogenreceptorn i normalt kolonepitel. READ MORE

5. 4. The effects of IRAP-inhibitors in the brain

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Dennis Josefsson; [2021]
   Keywords : IRAP; insulin-regulated aminopeptidase; IRAP-inhibitors; memory disorders; neurogenerative diseases; cognitive impairments;

   Abstract : The increased understanding of underlying neurobiological processes and their connections to cognitive performance has opened new doors for novel therapeutic strategies that aim to prevent, and even reverse the effects of memory disorders, neurodegenerative diseases and other cognitive impairments. One of the new and exciting drug targets that has emerged as a result of this research is insulin-regulated aminopeptidase (IRAP). READ MORE

6. 5. Internalisation of antigen-adjuvant conjugate in human dendritic cells : An assay development for using live cell imaging

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Linnéa Gustafsson; [2021]
   Keywords : cancer vaccine; coating; dendritic cells; immobilisation; internalisation; live cell imaging;

   Abstract : Introduction: Cancer vaccines are a therapeutic approach to initiate an antigen specific cytotoxic immune responses against tumors. Cancer vaccines are composed by an antigen (tumor peptide) and adjuvant. READ MORE