Essays about: "Dried blood spots"

Found 4 essays containing the words Dried blood spots.

  1. 1. Microfluidic blood fractionation and lysis towards analysis of cytokine levels in red blood cells

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Laura Barrett; [2019]
    Keywords : Microfluidics; Capillary action; Blood; Fractionation; Cytokine; Interleukin 3;

    Abstract : In the process of blood analysis, for biomarker detection, blood plasma or serumis analyzed, while Red blood cells (RBCs) are usually considered waste. A recentstudy has found that cytokine concentrations in RBC lysate are on average 12-fold higher than in plasma. READ MORE

  2. 2. Design of an LC-MS/MS method for measuring concentrations of Cyclosporine A and Tacrolimus from dried blood spots

    University essay from Uppsala universitet/Avdelningen för analytisk farmaceutisk kemi

    Author : Anna Hansson; [2015]
    Keywords : LC-MS MS; Dried blood spots; Immunosuppressive drugs;

    Abstract : Patients that have undergone organ transplantation are life-long treated with immunosuppressant drugs and these have to be monitored regularly to get the desired effect of suppressing the immune system. To monitor the drug concentration normally a venous blood sample is collected at a clinic but the use of dried blood spots (DBS) as a matrix for drug monitoring for immunosuppressant drugs will make home sampling possible for this patient group. READ MORE

  3. 3. Development and evaluation of procedures and reagents for extraction of proteins from dried blood spots for analysis using Proseek

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Johan Björkesten; [2014]
    Keywords : DBS; dried blood spots; PEA; Proseek; Proseek Multiplex; qPCR; Protein detection; Olink;

    Abstract : A method for extraction of proteins from dried blood spots (DBS) for analysis using Proseek is developed and evaluated. DBS, as sample format, possesses a number of desirable advantages over for example plasma samples. These advantages include for example minimal patient invasiveness, sampling simplicity and non regulated sample transportation. READ MORE

  4. 4. Extraction of therapeutic proteins from dried blood spots and their analysis on Gyrolab

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Hanna Garbergs; [2011]
    Keywords : Dried blood spots; immunoassays; therapeutic proteins; monoclonal antibodies; Gyrolab;

    Abstract : A method for extraction of therapeutic proteins from dried blood spots (DBS) followed by quantification on Gyrolab(TM) has been developed. The method makes it possible to measure the concentration of the analyte in the range 100-6000 ng/mL. The procedure can generate full analytical information from 15 μL blood originally sampled from a subject. READ MORE