Essays about: "Drug Combination"
Showing result 1 - 5 of 83 essays containing the words Drug Combination.
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1. Exploring alternative surfactants to replace PEG within lipid nanoparticles
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master); Lunds universitet/Bioteknik (CI); Lunds universitet/Bioteknik (master)Abstract : Over the past decade an increasing amount of studies has demonstrated that PEGylation not only precipitates reductions in drug delivery efficiency but also triggers the immune system to produce antibodies, specifically anti-PEG antibodies. The objective of my thesis is to explore alternative surfactants that could viably replace PEG within lipid nanoparticles. READ MORE
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2. Combining Cell Painting, Gene Expression and Structure-Activity Data for Mechanism of Action Prediction
University essay from Uppsala universitet/Nationellt resurscentrum för biologi och bioteknikAbstract : The rapid progress in high-throughput omics methods and high-resolution morphological profiling, coupled with the significant advances in machine learning (ML) and deep learning (DL), has opened new avenues for tackling the notoriously difficult problem of predicting the Mechanism of Action (MoA) for a drug of clinical interest. Understanding a drug's MoA can enrich our knowledge of its biological activity, shed light on potential side effects, and serve as a predictor of clinical success. READ MORE
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3. Analyzing the performance of active learning strategies on machine learning problems
University essay from Uppsala universitet/Avdelningen för systemteknikAbstract : Digitalisation within industries is rapidly advancing and data possibilities are growing daily. Machine learning models need a large amount of data that are well-annotated for good performance. To get well-annotated data, an expert is needed, which is expensive, and the annotation itself could be very time-consuming. READ MORE
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4. Evaluation of different block-copolymer coatings of iron oxide nanoparticles by flash nanoprecipitation
University essay from KTH/Fiber- och polymerteknologiAbstract : Nanopartiklar (NP) erbjuder unika möjligheter för medicinska tillämpningar, inklusive kontrollerad frisättning av cancerläkemedel, användning som bildkontrast vid avbildningsprocedurer eller hypertermisk behandling av cancerceller. Flash nanoprecipitation (FNP) producerar NPs för att kombinera dessa tillämpningar i en snabb, billig och skalbar beläggningsprocess. READ MORE
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5. Comparison of properties on Orally Disintegrating Tablets (ODTs) produced by direct compression or fluid bed granulation
University essay from Lunds universitet/Livsmedelsteknik och nutrition (master)Abstract : Orally disintegrating tablets (ODTs) is a popular drug delivery system as they dissolve in the mouth, usually within seconds which enables easy medication for patients with problem swallowing. In this thesis properties of ODTs were compared when produced with direct compression of the excipients or the excipients were pretreated to form granules in a fluid bed granulator prior to tableting. READ MORE