Essays about: "Drug Discovery"

Showing result 1 - 5 of 61 essays containing the words Drug Discovery.

  1. 1. Developing and validating assay-ready HEK-Blue CD40L cells : For a more flexible and faster screening of Affibody® molecules

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Erika Könberg; [2022]
    Keywords : cell biology; assay-ready cells; HEK-Blue cells;

    Abstract : Cell assay that evaluates a biologics’ potency and efficacy is an important part in the discovery and development of drug candidates. However, it requires regular maintenance of cell cultures, and the cell assays can only be performed when the cells have reached 70-80% confluency. READ MORE

  2. 2. The differential signalling of the succinate receptor SUCNR1/GPR91, through Gi versus Gq

    University essay from Lunds universitet/Teknisk mikrobiologi

    Author : Sofie Liljewall; [2022]
    Keywords : GPR91; SUCNR1; G protein recruitment; Gi; Gq; TRUPATH biosensor; BRET2; Applied Microbiology; Biology and Life Sciences;

    Abstract : G protein-coupled receptors are the biggest family of membrane bound receptor in the human genome, they are also target for many drugs due to their accessible location in the cell membrane. We have characterized the G protein recruitment of the succinate receptor 1 (SUCNR1/GPR91). READ MORE

  3. 3. Exploratory Analysis of Isoelectric Point Prediction with Simple Feature Encoding

    University essay from KTH/Tillämpad fysik

    Author : Henrik Söderhielm; [2022]
    Keywords : Applied Physics; Biotechnology; Tillämpad Fysik; Bioteknolgi;

    Abstract : Proteomics is the large scale study of proteins in biological systems such as those found in human cells. The understanding of proteomes, i.e. the complete set of proteins expressed by an organism, has especially useful applications in the medical field such as genetic research and drug discovery. READ MORE

  4. 4. The dynamics of Swedish police interrogations with suspects of alcohol-related, drug-related and serious crimes

    University essay from Göteborgs universitet/Psykologiska institutionen

    Author : Hanna Zajac (fd Langer); [2021-03-15]
    Keywords : ;

    Abstract : The aim of the current study was to explore the nature of Swedish police interrogations with suspects of alcohol-related offenses, drug offenses and other, more serious offenses. The taxonomy developed by Kelly, Miller, Redlich and Kleinman in 2013, was employed to analyze the relation between technique usage, suspect cooperation, and confession/denial outcomes over time in 64 written police records. READ MORE

  5. 5. Generating molecular synthesis schemes : A deep learning approach to generate synthesizable molecules

    University essay from KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Author : Clarisse Descamps; [2021]
    Keywords : ;

    Abstract : One key challenge of drug discovery is the generation of molecules that can be synthesised in laboratories. This project studies a neural network architecture that generates reaction schemes by choosing initial reactants from a set of commercial compounds and determines the intermediate reactions until a final product is found. READ MORE