Essays about: "Drug screening"

Showing result 1 - 5 of 53 essays containing the words Drug screening.

1. 1. Screening of HETP test conditions and resin storage solutions for HIC

   University essay from Uppsala universitet/Analytisk farmaceutisk kemi

   Author : Lise-Lotte Ronnerfors; [2023]
   Keywords : Hydrophobic Interaction Chromatography; Pfizer Health AB; Column packing;

   Abstract : Hydrophobic interaction chromatography (HIC) is a common purification method for biological drug substances. For continuous monitoring the quality of the purification, a column performance test is carried out to test the packing of the resin. READ MORE

3. 2. Intersecting Graph Representation Learning and Cell Profiling : A Novel Approach to Analyzing Complex Biomedical Data

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Nima Chamyani; [2023]
   Keywords : Graph representation learning; Cell profiling; Biological systems; Network medicine; Graphs; Machine learning techniques; Graph neural networks GNNs ; Protein-Compound-Pathway interactions; Biomarkers; Drug discovery;

   Abstract : In recent biomedical research, graph representation learning and cell profiling techniques have emerged as transformative tools for analyzing high-dimensional biological data. The integration of these methods, as investigated in this study, has facilitated an enhanced understanding of complex biological systems, consequently improving drug discovery. READ MORE

4. 3. Predicting morphological effect of compounds on COVID-19 infected cells

   University essay from Uppsala universitet/Läkemedelsdesign och läkemedelsutveckling

   Author : Viktor Öhrner; [2023]
   Keywords : QSAR; ML; AI; bioinformatics; COVID-19; morphological profiles;

   Abstract : The cost of developing new drugs is high and the aim of computer-assisted drug discovery is to reduce that development cost, either through virtual screening or generating novel compounds. System biology is one approach to drug discovery where the response of a biological system is the subject of study, instead of drug target interaction. READ MORE

5. 4. The impact of addition of force control agent in adhesive mixtures : Effect of magnesium stearates on flowability and aerosolization properties

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Moa Erlandsson; [2023]
   Keywords : ;

   Abstract : When drugs need to be delivered to the respiratory system dry powder inhalers (DPIs) are often used. The powders in DPIs often consists of a micronized active pharmaceutical ingredient (API) that is adhered to a larger carrier particle forming an adhesive mixture. READ MORE

6. 5. Compounds screening for the identification of novel drug to improve the Knock in efficiency mediated by CRISPR-Cas9

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Evangelia Anagnostou; [2023]
   Keywords : Genome editing; Knock in; HDR; CRISPR-Cas9; screening; NHEJ;

   Abstract : Genome editing is an exciting field that allows for the precise modification of an organism's DNA. One of the most advanced tools in this area is CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated protein 9), which creates a DSB (Double-strand break) at a specific location in the genome. READ MORE