Essays about: "ECFP"

Found 2 essays containing the word ECFP.

1. 1. Multi-task regression QSAR/QSPR prediction utilizing text-based Transformer Neural Network and single-task using feature-based models

   University essay from Linköpings universitet/Statistik och maskininlärning

   Author : Spyridon Dimitriadis; [2021]
   Keywords : multi-task regression; QSAR; QSPR; deep learning; attention based models; transfer learning;

   Abstract : With the recent advantages of machine learning in cheminformatics, the drug discovery process has been accelerated; providing a high impact in the field of medicine and public health. Molecular property and activity prediction are key elements in the early stages of drug discovery by helping prioritize the experiments and reduce the experimental work. READ MORE

3. 2. Fluorescent fusion proteins as probes to characterize tau fibril polymorphism

   University essay from Linköpings universitet/Kemi

   Author : Max Lindberg; [2019]
   Keywords : Alzheimer’s disease AD ; amyloids; FRET; tau; MAPT; fibrillation kinetics; seeding; fusion protein; EGFP; ECFP; EYFP; ThT; X-34; BTD14;

   Abstract : Alzheimer's disease (AD) is a large and growing problem and while we today lack a full understanding of this disease, we know that the protein tau and the amyloid fibrils it forms play a central role in its development. We also know that these fibrils can have different morphologies in different diseases and that fibrils produced in vitro not necessarily adopt any of the morphologies found in patients. READ MORE