Essays about: "EGFR"
Showing result 1 - 5 of 12 essays containing the word EGFR.
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1. Evaluating targeted combination therapies in EGFR wild-type non-small-cell lung cancer using mass spectrometry-based proteomics
University essay from Lunds universitet/Institutionen för immunteknologiAbstract : Survival for non-small cell lung cancer (NSCLC) patients has been significantly improved by epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with EGFR mutations. However, certain subpopulations of NSCLC patients with EGFR wild-type (wt) status have been shown to also respond to EGFR-TKIs. READ MORE
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2. The Effects of ACK1 and Cell Density on ErbB3
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : The ErbB family of receptors are involved in signalling relating to cell proliferation and differentiation through activation of pathways such as PI3K and MAPK. Their overexpression is often found in different cancer types and therefore, their expression is under tight regulation. READ MORE
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3. The Classification of Kinase Inhibitors on Five Channel Cell Painting Data Using Deep Learning
University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskapAbstract : Purpose This project aims to explore the classification method of kinase inhibitors with five-channel cell painting image data based on the deep learning model. Methods A ResNet50 transfer learning model was used as the starting point to build the deep neural network (DNN) model, where different DNN parameters were selected to make the deep learning model more suitable for the cell painting data. READ MORE
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4. Novel biomarkers in Pulmonary Hypertension : The correlation between ADMA, SDMA, L-arginine and disease progression and kidney function
University essay from Umeå universitet/FarmakologiAbstract : .... READ MORE
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5. EXPRESSION OF THE THREE PROTO-ONCOGENES, EGFR, MEK AND B-RAF AFTER TRANSFECTION INTO HUMAN CELLS AND THEIR DETECTION BY MASS SPECTROMETRY
University essay from Malmö högskola/Fakulteten för hälsa och samhälle (HS)Abstract : When activated by growth factors and mitogens, cellular receptors like EGFR become activated and transmit signals from the cell surface through the MAPK pathway into the nucleus of the cell, in order to elicit a cellular response like growth, apoptosis, proliferation, and survival. Over activation of EGFR even without receptor binding and members of the MAPK pathways like BRAF and MEK1 have been reported in tumorigenesis. READ MORE
