Essays about: "EGFR"

Showing result 1 - 5 of 11 essays containing the word EGFR.

  1. 1. The Effects of ACK1 and Cell Density on ErbB3

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Julia Svensson; [2021]
    Keywords : ;

    Abstract : The ErbB family of receptors are involved in signalling relating to cell proliferation and differentiation through activation of pathways such as PI3K and MAPK. Their overexpression is often found in different cancer types and therefore, their expression is under tight regulation. READ MORE

  2. 2. The Classification of Kinase Inhibitors on Five Channel Cell Painting Data Using Deep Learning

    University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Author : Ximeng Yang; [2021]
    Keywords : Deep Neural Network; Transfer Learning; Cell Painting; Kinase Inhibitor; Five Channel Image;

    Abstract : Purpose This project aims to explore the classification method of kinase inhibitors with five-channel cell painting image data based on the deep learning model. Methods A ResNet50 transfer learning model was used as the starting point to build the deep neural network (DNN) model, where different DNN parameters were selected to make the deep learning model more suitable for the cell painting data. READ MORE

  3. 3. Novel biomarkers in Pulmonary Hypertension : The correlation between ADMA, SDMA, L-arginine and disease progression and kidney function

    University essay from Umeå universitet/Farmakologi

    Author : Carina Wedegren; [2017]
    Keywords : pulmonary arterial hypertension; ADMA; SDMA; L-arginine; s-creatinine; eGFR;

    Abstract : .... READ MORE

  4. 4. EXPRESSION OF THE THREE PROTO-ONCOGENES, EGFR, MEK AND B-RAF AFTER TRANSFECTION INTO HUMAN CELLS AND THEIR DETECTION BY MASS SPECTROMETRY

    University essay from Malmö högskola/Fakulteten för hälsa och samhälle (HS)

    Author : Jimmy Olum; [2016]
    Keywords : EGFR; MEK1; BRAF; Mass spectrometry; Gateway Technology; pLenti 6.3 V5.;

    Abstract : When activated by growth factors and mitogens, cellular receptors like EGFR become activated and transmit signals from the cell surface through the MAPK pathway into the nucleus of the cell, in order to elicit a cellular response like growth, apoptosis, proliferation, and survival. Over activation of EGFR even without receptor binding and members of the MAPK pathways like BRAF and MEK1 have been reported in tumorigenesis. READ MORE

  5. 5. The genetics of glioma : and the use of dogs as model for human glioma

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Vanja Börjesson; [2016]
    Keywords : c-MET; canine; gene therapy; genome wide association studies GWAS ; next generation sequencing NGS ; glioma;

    Abstract : Glioma is the most common type of primary brain tumor in humans, and the second most common in canines. This tumor type originates from glial cells in the brain and is a genetic disorder caused by mutations in genes regulating important cellular functions. The current diagnosis of glioma is based on histopathological evaluations and gradings. READ MORE