Essays about: "EGFR"
Showing result 6 - 10 of 12 essays containing the word EGFR.
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6. The genetics of glioma : and the use of dogs as model for human glioma
University essay from SLU/Dept. of Animal Breeding and GeneticsAbstract : Glioma is the most common type of primary brain tumor in humans, and the second most common in canines. This tumor type originates from glial cells in the brain and is a genetic disorder caused by mutations in genes regulating important cellular functions. The current diagnosis of glioma is based on histopathological evaluations and gradings. READ MORE
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7. Analysis of PIK3CA mutations in tumours from patients with non-small cell lung cancer using pyrosequencing
University essay from Uppsala universitet/Institutionen för kvinnors och barns hälsaAbstract : A subgroup of non-small cell lung cancer (NSCLC) cases harbour mutations in classical oncogenes, which can affect therapy response and prognosis. By therapeutically targeting the corresponding proteins with inhibitory drugs, the clinical outcome for these lung cancer patients may be improved. READ MORE
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8. Process development for the production of a therapeutic Affibody® Molecule
University essay from Institutionen för biologisk grundutbildningAbstract : Recently HER3, member of the epidermal growth factor receptor family (EGFR), has been found to play a crucial role in the development of resistance towards inhibitors that are given to patients with HER1- and HER2-driven cancers. As HER3 is up-regulated or over-activated in several types of human cancers, it is of outmost importance that new innovative drugs target its oncologic activity. READ MORE
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9. The importance og LRIG1 in lung cancer
University essay from OnkologiAbstract : .... READ MORE
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10. Genetic heterogeneity of EGFR and KRAS mutations in primary tumor tissue from non-small cell lung cancer patients
University essay from Institutionen för medicinsk biokemi och mikrobiologiAbstract : Activated epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations characterize molecular subgroups of non-small cell lung cancer (NSCLC) and have a strong predictive value for response to EGFR inhibitor therapy. Recently, EGFR mutation testing was included in the diagnostic algorithm of NSCLC. READ MORE