Essays about: "Frank Nylén"

Found 1 essay containing the words Frank Nylén.

  1. 1. Development of a reporter gene assay for PXR mediated CYP3A4 induction

    University essay from Institutionen för fysik, kemi och biologi

    Author : Frank Nylén; [2008]
    Keywords : CYP3A4; induction; reporter gene assay;

    Abstract : PXR mediated elevation of CYP3A4 expression is a costly problem in drug development as well as a clinical problem due to clinically important drug interactions caused by the enzyme induction. CYP3A4 is responsible for the metabolism of more than 50% of the drugs commonly used today. Many of these, as well as other compounds e.g. READ MORE