Essays about: "Fredrik Kristoffersson"

Found 3 essays containing the words Fredrik Kristoffersson.

  1. 1. Expression of the heparan sulfate biosynthesis enzymes NDST1 and NDST2 and their major splice variants in human tissues.

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Fredrik Kristoffersson; [2018]
    Keywords : Heparan sulfate; NDST; glycobiology; N-Deacetylase And N-Sulfotransferase; NGS; bioinformatics;

    Abstract : The aim of the study was to investigate the expression NDST transcripts in a wide variety of tissues using RNA-sequencing experimental data from five published studies, using two common in silico tools: the Tophat-Cufflink pipeline and the HTSeq-DEXSeq pipeline. We show that to detect NDST alternative transcripts, paired-end sequencing should be used with replicates of samples or conditions together with 100 base read length to allow for reliable detection of the low expressed transcripts in the NDST family. READ MORE

  3. 2. A  smart beta investment strategy to make risk more transparent : A quantitative study as a contribute to lowering the systemic risk, without sacrifice of return.

    University essay from Mittuniversitetet/Avdelningen för ekonomivetenskap och juridik

    Author : Fredrik Kristoffersson; [2017]
    Keywords : Smart beta; smart beta strategy; portfolio strategy; risk transparency; indexing investing; CAPM; Stockholmsbörsen; systemic risk;

    Abstract : This study have focused on the creation of a smart beta investment strategy to make risks in terms of beta for individual assets more transparent, and to explore if the constructed portfolios risk in terms of standard deviation significantly gets lower than for different benchmark indexes. The strategy could be used for investors who want to decrease their contribution to systemic risk, without sacrificing return. READ MORE

  4. 3. Novel target genes of ZEB1 and Snail1 in triple-negative human breast cancer.

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Fredrik Kristoffersson; [2016]
    Keywords : TGF-beta; cancer; breast cancer; biochemistry; EMT;

    Abstract : Breast cancer is comprised of several subtypes that are different from one another and thedivergence leads to different outcomes of the disease. There are known prognostic factors andphenotypic distinction in different biological factors and expression patterns, such as theestrogen receptor (ER), progesterone receptor (PR), Ki67, HER2/neu expression (HER2). READ MORE