Essays about: "Frieder Henning"

Found 2 essays containing the words Frieder Henning.

  1. 1. Analysis of HLA-A, -B and -DR Alleles as Risk Factors for One-Year Mortality in Heart Transplants Using Artificial Neural Networks

    University essay from Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation; Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Author : Frieder Henning; [2017]
    Keywords : deep learning; HLA; heart transplant; risk factor; one-year mortality; artificial neural network; Physics and Astronomy;

    Abstract : The beneficial effects of HLA matching at the HLA-A, -B and -DR loci on recipient short- and long-term survival in heart transplants have been established in a number of studies. The objective of the present study was to evaluate the importance of individual HLA alleles at the HLA-A, -B and -DR loci as risk factors for recipient death within one year after transplant by using artificial neural networks. READ MORE

  3. 2. DERIVATION OF A REWEIGHTING ALGORITHM FOR THE PREDICTION OF THE THERMODYNAMIC STABILITY OF MUTATED SEQUENCES AND EVALUATION OF ITS USABILITY IN A SIMPLE CONTINUOUS PROTEIN MODEL

    University essay from Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Author : Frieder Henning; [2015]
    Keywords : Physics and Astronomy;

    Abstract : In this thesis, a new reweighting algorithm for predicting the native conformations of amino acid sequences, consisting of 16 residues in a reduced representation continuous protein model, is derived and tested to map neutral nets of α-helices and β-sheets. For examining the potential of the reweighting algorithm for predicting the thermodynamic stability of amino acid sequences, it is applied to a mutational pathway, connecting a α-helix to a β-sheet. READ MORE