Essays about: "GSEA"

Found 3 essays containing the word GSEA.

  1. 1. Transcriptional basis of Huntington’s Disease: Gene expression analysis indicate increased immune responses in the brain and mitochondrial dysfunction in adipose tissues of HD model mouse

    University essay from KTH/Proteinvetenskap

    Author : Intisar Salim; [2023]
    Keywords : Huntington’s Disease; mRNA-seq; tissue specific gene expression; cerebrospinal fluid; biomarker; Huntingtons sjukdom; mRNA-seq; vävnadsspecifik genexpression; cerebrospinalvätska; biomarkör;

    Abstract : Huntingtons sjukdom (HD) är ett neurodegenerativt tillstånd som orsakas av mutationer i huntingtin gen (Htt), och resulterar till upprepade glutamin (polyQ) i Htt-proteinet. Muterad Htt kan inte vika sig ordentligt och börjar därför aggregera i celler. READ MORE

  3. 2. Comparative study of topology based pathway enrichment analysis methods for cardiac hypertrophy from a stem cell model using : ToPASeq and EnrichmentBrowser packages

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Georgia Fru Mbah-Mbole; [2020]
    Keywords : ;

    Abstract : Pathway enrichment analysis is an approach extensively used when analyzing high throughput data to identify pathways enriched within a group of differentially expressed genes. Furthermore, different methods utilizing the topology of the pathway offer a unique way of analyzing and interpreting gene expression data. READ MORE

  4. 3. Knowledge Based Gene Set analysis (KB-GSA) : A novel method for gene expression analysis

    University essay from Institutionen för vård och natur

    Author : Trishul Jadhav; [2010]
    Keywords : Gene set analysis; functional enrichment analysis;

    Abstract : Microarray technology allows measurement of the expression levels of thousand of genes simultaneously. Several gene set analysis (GSA) methods are widely used for extracting useful information from microarrays, for example identifying differentially expressed pathways associated with a particular biological process or disease phenotype. READ MORE