Essays about: "GWAS"

Showing result 11 - 15 of 30 essays containing the word GWAS.

  1. 11. Genome-wide association study to find SNPs associated with circulating levels of the protein FGF-21

    University essay from Umeå universitet/Institutionen för fysik

    Author : Rebecca Risslén; [2020]
    Keywords : GWAS;

    Abstract : Colorectal cancer (CRC) is one of the most common types of cancer globally. In Sweden, every year over 6000 individuals are diagnosed with CRC making it the fourth most common form of cancer in the country. The symptoms of the disease occur late in its development, therefore diagnosis is often delayed, which has a negative effect on mortality. READ MORE

  3. 12. Is it possible to improve the bovine immune response to mastitis using immunogenetics?

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Emelie Björnhagen; [2019]
    Keywords : bovine; immunology; genetics; breeding; mastitis;

    Abstract : Mastitis is a major problem for cows all over the world. For decades selection against mastitis has been performed through direct and indirect selection. Favorable outcomes of reduced mastitis incidence include: Economic gains, reduced use of antibiotics as well as improved animal welfare. READ MORE

  4. 13. Disease modules identification in heterogenous diseases with WGCNA method

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Naseem Ullah; [2019]
    Keywords : disease module; WGCNA; parameter settings;

    Abstract : The widely collected and analyzed genetic data help in understanding the underlying mechanisms of heterogeneous diseases. Cellular components interact in a network fashion where genes are nodes and edges are the interactions. READ MORE

  5. 14. Validation of the role of a SNP in the VPS35 gene and its effect on non-co-agulating milk in Swedish Red Cattle

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Gro Hylén; [2018]
    Keywords : VPS35; genotype; SNP; SR; cow; NC-milk; MCP; genomic selection;

    Abstract : From earlier studies, it is clear that nearly 20 % of the Swedish red (SR) dairy herd possess milk that doesn’t coagulate within 40 minutes after rennet addition. This is a problem when processing milk into cheese because lower cheese yield is the result of non-coagulating (NC) milk. An estimate of 17. READ MORE

  6. 15. A canonical correlation analysis- based approach to identify causal genes in atherosclerosis

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Crisencia Sizyoogno; [2018]
    Keywords : Canonical correlation analysis; Atherosclerosis; bioinformatics; CRISPR_Cas9; Phenotypes; Genotypes; GWAS; zebrafish; Cardiovascular and metabolic disease;

    Abstract : Genome-wide associations studies (GWASs) have identified hundreds of loci that are strongly associated with coronary artery disease and its risk factors. However, the causal variants and genes remain unknown for the vast majority of the identified loci. READ MORE