Essays about: "Gene set analysis"

Showing result 1 - 5 of 41 essays containing the words Gene set analysis.

  1. 1. Pseudomonas aeruginosa gene expression analysis using pangenome and PAO1 reference genomes

    University essay from Lunds universitet/Examensarbeten i bioinformatik

    Author : Yi Su; [2023]
    Keywords : Biology and Life Sciences;

    Abstract : Development in sequencing technologies has made the analyses of genetic material much more accessible. Processing sequenced data for an accurate analysis comes with its challenges, especially with the studies in microbial in clinical in vivo samples where difficulties in the collection of these samples for sequencing could lower the quality and contamination from the human host which might affect the accuracy of downstream analysis. READ MORE

  3. 2. Developing a reproducible bioinformatics workflow for canine inherited retinal disease

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Melina Toni Marie Martin; [2023]
    Keywords : CanFam4; Nextflow; Inherited Retinal Degeneration; dog; whole-genome sequencing; bioinformatics;

    Abstract : Inherited Retinal Degenerations (IRDs) are a heterogenous group of diseases which lead to vision impairment and can be found both in humans and in dogs. About 1 in 1,380 humans is estimated to suffer from an autosomal recessive IRD, which would be 5.5 million people worldwide, and many more are estimated to be unaffected carriers. READ MORE

  4. 3. Transcriptional basis of Huntington’s Disease: Gene expression analysis indicate increased immune responses in the brain and mitochondrial dysfunction in adipose tissues of HD model mouse

    University essay from KTH/Proteinvetenskap

    Author : Intisar Salim; [2023]
    Keywords : Huntington’s Disease; mRNA-seq; tissue specific gene expression; cerebrospinal fluid; biomarker; Huntingtons sjukdom; mRNA-seq; vävnadsspecifik genexpression; cerebrospinalvätska; biomarkör;

    Abstract : Huntingtons sjukdom (HD) är ett neurodegenerativt tillstånd som orsakas av mutationer i huntingtin gen (Htt), och resulterar till upprepade glutamin (polyQ) i Htt-proteinet. Muterad Htt kan inte vika sig ordentligt och börjar därför aggregera i celler. READ MORE

  5. 4. Capturing genes with high impact based on reconstruction errors produced by variational autoencoders

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Utz Lovis Rieger; [2023]
    Keywords : ;

    Abstract : In this work we present a novel method to extract potential hub genes, transcription factors and regions with densely interconnected protein-protein-interaction networks from RNAseq data. To achieve this we deploy variational autoencoders, a generative machine learning framework, and extract the gene-wise reconstruction errors. READ MORE

  6. 5. Saponiner i ärta : biosyntes av soyasaponiner och dess genetiska mekanismer i ärtväxter

    University essay from SLU/Dept. of Plant Breeding (from 130101)

    Author : Ines Falk Tingström; [2022]
    Keywords : Pisum sativum; baljväxter; Fabaceae; proteingrödor; växtförädling; jämförande genomik;

    Abstract : Efterfrågan på proteinrika vegetabiliska livsmedel ökar och intresse finns från både konsument, politiker och industri att använda svenskodlade råvaror i större utsträckning. Ärta (Pisum sativum L. READ MORE