Essays about: "Gyrolab Bioaffy"

Found 3 essays containing the words Gyrolab Bioaffy.

  1. 1. Effects of antibody labeling chemistry on assays developed for the Gyrolab immunoassay platform

    University essay from Uppsala universitet/Molekylär systembiologi

    Author : Julia Dencker; [2021]
    Keywords : Antibodies; Labeling chemistry; Site-specific labeling; Immunoassay; Gyrolab;

    Abstract : The aim of this project was to make a comparison of the effects of antibody labeling chemistries on assays developed for the Gyrolab immunoassay platform. One of the labeling techniques was a heterogenous labeling technique targeting amino groups on the antibody. READ MORE

  3. 2. Microscale measurement of kinetic binding properties of monoclonal antibodies in solution using Gyrolab

    University essay from Institutionen för biologisk grundutbildning

    Author : Fredrik Johansson; [2011]
    Keywords : Affinity; association rate constant; Bioaffy; characterization; Gyrolab; immunoassay; kinetics; microfluidics; monoclonal antibody; screening;

    Abstract : The number of monoclonal antibodies approved for therapeutic use has increased rapidlyover the last decade. As a consequence, precise and robust kinetic characterization techniquesare crucial in order to select the best suitable candidates. A kinetic characterization methodwas developed in Gyrolab with automated sample transfers. READ MORE

  4. 3. Determination of antibody affinity and kinetic binding constants in Gyrolab Bioaffy microfluidic CD

    University essay from Institutionen för fysik, kemi och biologi

    Author : Mikael Karlsson; [2008]
    Keywords : Affinity constants; Equilibrium dissociation constants; Kinetic rate constants; Immunoassay; Monoclonal antibodies; Microfluidics; Gyrolab Bioaffy; Microlaboratory; Compact disc;

    Abstract : Studies of binding reactions are of highest importance in a vast number of areas of biomedicine and biotechnology. A demand for fast and accurate small-volume measurements grows stronger, partly due to the development of therapeutic antibodies. In this report, a novel method for studies of binding reactions of antibodies is described. READ MORE