Essays about: "HLA"

Showing result 1 - 5 of 23 essays containing the word HLA.

  1. 1. Identification of Immunological Targets for Brain Cancer Immunotherapy

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Zhenda Wang; [2022]
    Keywords : Cancer immunotherapy; brain cancer; neoantigen; MHC HLA; TCR;

    Abstract : Background Cancer immunotherapy has yielded many successes. Yet to some hard-to-treat brain tumors, such as glioblastoma multiforme (GBM) and diffuse intrinsic pontine glioma (DIPG), it still lacks substantial improvement. Neoantigens resulting from mutations in malignant cells are the key targets for employing adoptive cell therapies. READ MORE

  2. 2. Synchronous vs Asynchronous calls and Flow Control for HLA 4

    University essay from Linköpings universitet/Institutionen för datavetenskap

    Author : David Frisén; [2022]
    Keywords : HLA; Federate Protocol; Synchronous; Asynchronous;

    Abstract : HLA is a standard for distributed simulations where many small simulations connect to each other to create a bigger simulation. As networking technologies have evolved the requirements for the simulations. This includes running certain simulations to communicate over Wide Area, 4G, and 5G networks. READ MORE

  3. 3. Structural features underlying antigen presentation by the non-classical MHC class Ib molecule Qa-1b

    University essay from KTH/Proteinvetenskap

    Author : Lejla AI-Tamimi; [2022]
    Keywords : immune checkpoint; NKG2A; MHC class Ib; Qdm; antibody; crystal structure;

    Abstract : Blockering av NKG2A receptorn på NK - och CD8+ T celler med en anti-NKG2A antikropp, medför en aktivering av cytolytisk aktivitet, och är en lovande immunkontrollpunkt i immunterapi mot cancer. Nyligen har en TCR-liknande antikropp, EXX1, som binder till liganden för NKG2A receptorn, Qa-1b - en icke-klassisk MHC klass Ib molekyl i möss -studerats i tumör modeller in vitro. READ MORE

  4. 4. Temporal Sparse Encoding and Decoding of Arrays in Systems Based on the High Level Architecture Standard

    University essay from Linköpings universitet/Institutionen för datavetenskap

    Author : Viktor Severinsson; Johan Thörnblom; [2022]
    Keywords : Sparse Encoding; Temporal Sparse Encoding; HLA; High Level Architecture;

    Abstract : In this thesis, a method for encoding and decoding arrays in systems based on the standard High Level Architecture is presented. High Level Architecture is a standard in the simulation industry, which enables interoperability between different simulation systems. READ MORE

  5. 5. Unraveling gene gene interactions in rheumatoid arthritis

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Saad Salman Khan Lodhi; [2021]
    Keywords : ;

    Abstract : Rheumatoid arthritis (RA) is a systematic autoimmune disorder characterized by a persistent joint inflammation. A subset of HLA-DRB1 alleles known as shared epitope (SE) are the strongest genetic risk factors to develop anti-citrullinated protein antibody positive (ACPA-positive) RA. READ MORE