Essays about: "Hanna Sädbom-Williams"

Found 1 essay containing the words Hanna Sädbom-Williams.

  1. 1. When the brain loses TrkBactivation : The effects of ketamine on BDNF-TrkB neurotransmission in animal models of depression

    University essay from Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Author : Hanna Sädbom-Williams; [2021]
    Keywords : Ketamine; Depression; BDNF; TrkB; Animal model; Hippocampus; Prefrontal cortex;

    Abstract : Ketamine is a non-competitive N-methyl-D-aspartate (NMDA)-channel blocker that has recently shown promise in the treatment of major depressive disorder, distinguishing itself from classical anti-depressants through its rapid and lasting effects when given at sub-anaesthetic doses. Animal models of depression are commonly used to research individual mechanisms of action and this literature review aimed to investigate how ketamine influences BDNF-TrkB neurotransmission in the hippocampus and prefrontal cortex within animal models of depression. READ MORE