Essays about: "Heterodimerization"
Found 2 essays containing the word Heterodimerization.
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1. Orphan G-Protein Coupled Receptors : Can we deorphanize the remaining orphans despite all the challenges?
University essay from Linköpings universitet/Institutionen för fysik, kemi och biologiAbstract : G-protein coupled receptors (GPCRs) play a key role in a broad range of biological processes by binding to a wide variety of signaling molecules, which have resulted in 34% of all FDA-approved drugs which target GPCRs. The human genome encodes for approximately 800 GPCR members of which about 140 non-olfactory receptors remain orphans with an unknown function and endogenous ligand. READ MORE
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2. Correlations between unexplained infertility and single nucleotide polymorphism in the genes of leukemia inhibitory factor receptor and gp130
University essay from Institutionen för medicinsk biokemi och mikrobiologiAbstract : About 30 % of all infertile couples suffer from infertility of an unexplained cause. Leukemia inhibitory factor (LIF) is a glycoprotein produced by the endometrium and is an important cytokine in the implantation process. LIF exerts its biological functions through heterodimerization of its two receptors: LIF receptor (LIFR) and gp130. READ MORE