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Found 2 essays matching the above criteria.

1. 1. Systematic comparison of gene regulatory datasets using experimentally validated enhancers

   University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

   Author : Xue Dong; [2020]
   Keywords : Capture Hi-C; ChIP-seq; enhancer; promoter-enhancer interactions; eQTLs;

   Abstract : Promoter-enhancer interactions are essential for gene regulating, Capture Hi-C is a chromosome conformation capture method to map promoter-enhancer interactions at high resolution. We have Capture Hi-C data forGM12878 cells, immortalized primary B lymphocytes, in three replicates. READ MORE

3. 2. Identifying gene regulatory interactions using functional genomics data

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Annelie Johansson; [2014]
   Keywords : bioinformatics; gene regulation; promoter; enhancer; correlation; Hi-C data; DNase-seq;

   Abstract : Previously studies used correlation of DNase I hypersensitivity sites sequencing (DNase-seq) experiments to predict interactions between enhancers and its target promoter gene. We investigate the correlation methods Pearson’s correlation and Mutual Information, using DNase-seq data for 100 cell-types in regions on chromosome one. READ MORE