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Showing result 1 - 5 of 23 essays matching the above criteria.

  1. 1. Deacetylated Hyaluronan : Exploration of deacetylation techniques for hyaluronan (oligo and polysaccharides)

    University essay from Uppsala universitet/Institutionen för materialvetenskap

    Author : Sima Mardini; Hanna Björk; Marcus Möller; Carl Lagergren; Oscar Samuelsson; [2023]
    Keywords : hyaluronic acid; deacetylated hyaluronan; N-deacetylation; re-acetylation; hydrogels;

    Abstract : Hyaluronic acid is an organic polysaccharide with a wide range of uses in medical and cosmetic industries due to its physiological properties. Crosslinked hyaluronic acid is a commonly used filler agent because of its water retention capabilities. N-deacetylation can be performed to enable new derivatives of hyaluronic acid. READ MORE

  3. 2. Coacervates as a subcutaneous drug delivery system

    University essay from Uppsala universitet/Institutionen för läkemedelskemi

    Author : Dania Elkhalifa; [2022]
    Keywords : ;

    Abstract : Subcutaneous administration of biological drugs has become highly attractive as it offers the possibility for patient self-administration. Coacervates as a subcutaneous drug delivery system provide a way to decrease injection volumes thereby reducing the risk of injection site pain. READ MORE

  4. 3. Exploration of bioactive additives for hyaluronan based hydrogels : A literature study

    University essay from

    Author : Tilda Eriksson; Lisa Quakkelaar; Alexander Parkstam; Alina Karlsson; Mansourah Askari; Shukri Said Ahmed; [2022]
    Keywords : Hyaluronan; Hyaluronic Acid; HA; 1; 4-Butanediol diglycidyl ether; BDDE; polynucleotides; mannitol; biomedical applications; dermatological fillers; fillers; Hyaluronan; Hyaluronsyra; HA; 1; 4-butandiol diglycidyleter; BDDE; polynukleotider; mannitol; biomedicinska applikationer; dermatologiska fyllmedel; fyllmedel;

    Abstract : Hyaluronan (HA) is a substance that is commonly used in biomedical applications in the form of hydrogels. One of these biomedical applications is dermatological fillers where HA is cross-linked with 1,4-Butanediol diglycidyl ether (BDDE) to reduce its rapid turnover within tissue. The filler gives a volumetric effect that can fill out wrinkles. READ MORE

  5. 4. Hyaluronic Acid Hydrogel as a Scaffold for Cells’ Encapsulation

    University essay from Uppsala universitet/Institutionen för materialvetenskap

    Author : Susanna Wärmegård; [2022]
    Keywords : hyaluronic acid; hydrogel; 3D cell culture;

    Abstract : Hydrogels are high water-content polymers that mimic the extracellular matrix of cells. The polymers can have many sources and be of natural origin from the extracellular matrix (ECM) of cells or be synthetically derived. READ MORE

  6. 5. Promote neuroprotection and axonal outgrowth in the central and peripheral neural system

    University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi

    Author : Elin Petersson; [2021]
    Keywords : Spinal cord injury; interleukin-1 receptor antagonist; excitotoxicity; qPCR; dorsal root ganglion.;

    Abstract : Acute spinal cord injury is often caused by collisions with motor vehicles, falls or violence. This injury could potentially lead to paraplegia or tetraplegia, causing great economic and personal loss. The patophysiology is biphasic, with primary and secondary mechanisms. READ MORE