Essays about: "Immunocytochemistry"

Showing result 1 - 5 of 16 essays containing the word Immunocytochemistry.

1. 1. Characterisation and Identification of Human Mesenchymal Stromal Cells and the Impact of Different Culturing Media

   University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi

   Author : Sana Said Yahya; [2023]
   Keywords : Culturing media; Fetal bovine serum; Human serum; Cell proliferation; In-vitro differentiation;

   Abstract : Background: Mesenchymal stromal cells (MSCs) are multipotent cells that can differentiate into various cell types and possess immunomodulatory and anti-inflammatory effects, making them interesting candidates for therapeutic applications. MSCs are present in small quantities in tissues like bone marrow and therefore need to be expanded while preserving their essential characteristics. READ MORE

3. 2. Composite Cell Block As Control For Immunocytochemical Stains On Cytology Prepared Samples

   University essay from Uppsala universitet/Institutionen för medicinsk cellbiologi

   Author : Mariia Anastasiia Spireva; [2023]
   Keywords : ICC; formalin; PreservCyt®; agar; plasma-thrombin;

   Abstract : Cytopathology plays a significant role in cancer diagnostics. One of the ancillary methods used for prognostication is immunocytochemistry (ICC). Formalin pre-fixed tissue blocks are often used as validated immunohistochemical controls for cytology samples. READ MORE

4. 3. Investigation on Cell-Cell Junctions by Inhibition of Na,K-ATPase Activity

   University essay from KTH/Tillämpad fysik

   Author : Caroline Boström; [2021]
   Keywords : NaK-ATPase; Ouabain; Cell junctions; ECadherin; Occludin; Claudin7; Western Blot; Fluorescent Imaging; Tight junctions; Adherens Junctions; Immunocytochemistry; Ouabain; NaK-ATPase; ECadherin; Occludin; Claudin7; Western Blot; Immunocytokemi; Cellkontakter; Fluorescernsmikroskopi;

   Abstract : This thesis report investigates the effect on cellcell junction proteins when the Na,K-ATPase (NKA) is inhibited. The main goal is to develop an understanding of how the NKA activity regulates the cell junction proteins. The investigated proteins are the adherens junction protein ECadherin, and the tight junction proteins Occludin and Claudin7. READ MORE

5. 4. The effects of IRAP-inhibitors in the brain

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Dennis Josefsson; [2021]
   Keywords : IRAP; insulin-regulated aminopeptidase; IRAP-inhibitors; memory disorders; neurogenerative diseases; cognitive impairments;

   Abstract : The increased understanding of underlying neurobiological processes and their connections to cognitive performance has opened new doors for novel therapeutic strategies that aim to prevent, and even reverse the effects of memory disorders, neurodegenerative diseases and other cognitive impairments. One of the new and exciting drug targets that has emerged as a result of this research is insulin-regulated aminopeptidase (IRAP). READ MORE

6. 5. Investigation of endogenous p21 expression and its correlation to therapy resistance in high-risk neuroblastoma

   University essay from KTH/Proteinvetenskap

   Author : Agnes Sorteberg; [2021]
   Keywords : p21; high-risk neuroblastoma; small molecular inhibitor; chemo-resistance; combination treatment;

   Abstract : Neuroblastoma (NB) is a childhood cancer with a highly complex nature. High-risk NB patients undergo intensive treatment regimens that are often followed by long-term side effects. This, in addition to the emergence of resistant cancer cells, highlights a need for novel therapeutic targets and treatment strategies to improve outcome in NB. READ MORE