Essays about: "Immunogenicity"

Showing result 1 - 5 of 9 essays containing the word Immunogenicity.

1. 1. Characterization of Antigenic Properties of Two Immunogenic Proteins of Streptococcus pneumoniae 

   University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Author : Mawj Jasimalsalih; [2023]
   Keywords : Immunogenic Proteins; PrsA; MalX; Membrane Vesicles; Protein Properties; Streptococcus pneumoniae virulence factors;

   Abstract : The bacterium Streptococcus pneumoniae (pneumococcus), is considered to be a leading cause of morbidity and mortality globally, particularly in infants and the elderly. It is one of the most frequent causes of respiratory tract infections, which sporadically have the potential to develop into serious invasive symptoms including sepsis and meningitis. READ MORE

3. 2. Automated Decellularization of Heart Valves

   University essay from Lunds universitet/Avdelningen för Biomedicinsk teknik

   Author : Filip Nyberg; Brendan Carlson; [2022]
   Keywords : Technology and Engineering;

   Abstract : Abstract—For those living today with severely malfunctioning heart valves, replacement is the only available treatment. Patients are today typically offered either mechanical valves, xenograft or allograft. Decellularized heart valves have the potential of becoming one of the standard alternatives for such heart valve transplants. READ MORE

4. 3. Evaluation of the immunogenicity of SARS-CoV-2 B cell epitopes

   University essay from Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Author : Sofia Hogander; [2022]
   Keywords : SARS-CoV-2; peptide vaccine; B cell epitope; ELISA; solid phase peptide synthesis;

   Abstract : Background: The COVID-19 pandemic is caused by the SARS-CoV-2 virus, which enter the host cells through interactions between the receptor-binding domain (RBD) on the S-protein and the ACE-2 receptor on the host cell. A novel type of vaccine strategy is peptide vaccines, with great potential as a faster and more selective approach to conventional vaccine development. READ MORE

5. 4. Development of a reporter gene assay on an automated platform

   University essay from Lunds universitet/Beräkningskemi; Lunds universitet/Tillämpad biokemi

   Author : Fanny Redin; [2021]
   Keywords : Reporter gene assay; Automation; Svar Life Science; Immunogenicity; TNF-alpha; Applied biochemistry; Technology and Engineering; Biology and Life Sciences;

   Abstract : Biological drugs have the potential to trigger unwanted immunogenic responses in patients which might affect the efficacy and safety of the treatment. Evaluating the immunogenicity throughout the drug development process is therefore crucial. READ MORE

6. 5. Exosomes and lipid nanoparticles - the future of targeted drug delivery

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Sara Lundberg; Emelia Karlsson; Hugo Dahlberg; Mathilda Glansk; Sara Larsson; Sofia Larsson; Karl Carlsson; [2020]
   Keywords : Exosomes; lipid nanoparticles; drug delivery;

   Abstract : In this project an overview of how synthetic lipid nanoparticles and exosomes can be used for targeted drug delivery is compiled. The goal is to identify aspects that can be in favor for targeted drug delivery and the development of products at Cytiva. READ MORE