Essays about: "Individual Case Safety Reports"

Showing result 1 - 5 of 8 essays containing the words Individual Case Safety Reports.

  1. 1. Free-text Informed Duplicate Detection of COVID-19 Vaccine Adverse Event Reports

    University essay from Uppsala universitet/Avdelningen för systemteknik

    Author : Erik Turesson; [2022]
    Keywords : Duplicate detection; Deduplication; Record linkage; Adverse Event Reports; COVID-19 Vaccines; Uppsala Monitoring Centre; VigiBase; Machine Learning; Gradient Boosted Decision Trees; BERT; Natural Language Processing; Pharmacovigilance; Individual Case Safety Reports;

    Abstract : To increase medicine safety, researchers use adverse event reports to assess causal relationships between drugs and suspected adverse reactions. VigiBase, the world's largest database of such reports, collects data from numerous sources, introducing the risk of several records referring to the same case. READ MORE

  2. 2. Reaching Those ‘Out-of-Reach’: An Explorative Case-Study of Fire Prevention in Vulnerable Urban Communities within Copenhagen.

    University essay from Lunds universitet/Riskhantering (CI)

    Author : Aron Fransson; [2021]
    Keywords : Fire Prevention; Fire Rescue Services; Risk Communication; Fire Governance; Urban Vulnerable Communities; Community Risk Reduction; Technology and Engineering;

    Abstract : Considering the nature of vulnerability to fires and at-risk groups, the issue is arguably a social problem where spatial analysis has allowed for a greater context, beyond the individual, to be analyzed. Furthermore, reports from fire rescue services of local safety concerns and the convergence of interest between different stakeholders has made communities disposition to fire safety increasingly relevant. READ MORE

  3. 3. Creation of a Next-Generation Standardized Drug Groupingfor QT Prolonging Reactions using Machine Learning Techniques

    University essay from Uppsala universitet/Avdelningen för systemteknik

    Author : Jacob Tiensuu; Elsa Rådahl; [2021]
    Keywords : Pharmacovigilance; Adverse Drug Reactions; MedDRA; VigiBase; WHODrug Global; QT prolongation; Torsades de Pointes; Individual Case Safety Reports; Text Recognition; Standardised Drug Grouping; Multinomial Logistic Regression; BERT;

    Abstract : This project aims to support pharmacovigilance, the science and activities relating to drug-safety and prevention of adverse drug reactions (ADRs). We focus on a specific ADR called QT prolongation, a serious reaction affecting the heartbeat. Our main goal is to group medicinal ingredients that might cause QT prolongation. READ MORE

  4. 4. Improving the speed and quality of an Adverse Event cluster analysis with Stepwise Expectation Maximization and Community Detection

    University essay from Uppsala universitet/Institutionen för medicinska vetenskaper

    Author : Nils Erlanson; [2020]
    Keywords : Adverse Drug Reactions; Pharmacovigilance; Cluster Analysis; Stepwise Expectation Maximization; Community Detection; Topic Modelling;

    Abstract : Adverse drug reactions are unwanted effects alongside the intended benefit of a drug and might be responsible for 3-7\% of hospitalizations. Finding such reactions is partly done by analysing individual case safety reports (ICSR) of adverse events. The reports consist of categorical terms that describe the event. READ MORE

  5. 5. Investigating the scaleability of analyzing and processing RDBMS datasets with Apache Spark

    University essay from Uppsala universitet/Institutionen för informationsteknologi

    Author : Ferhat Bahceci; [2018]
    Keywords : ;

    Abstract : At the Uppsala Monitoring Centre (UMC), individual case safety reports (ICSRs) are managed, analyzed and processed for publishing statistics of adverse drug reactions. On top of the UMC’s ICSR database there is a data processing tool used to analyze the data. READ MORE