Essays about: "Kd"

Showing result 1 - 5 of 71 essays containing the word Kd.

  1. 1. Development of a PNA-drug conjugate for pretargeted delivery of cytotoxic drugs

    University essay from Uppsala universitet/Theranostics

    Author : Astrid Haraldsson; [2023]
    Keywords : PNA; pretargeting; cancer therapy; cytotoxic payload;

    Abstract : One of the major challenges in cancer treatment is delivering high enough doses of active substance specifically to cancer cells without accumulation in healthy organs. Pretargeting has emerged as a potential solution, where the delivery of a cancer recognizing (primary) agent and a cancer killing (secondary) agent are separated. READ MORE

  3. 2. Knowledge distillation for anomaly detection

    University essay from Uppsala universitet/Institutionen för informationsteknologi

    Author : Nils Gustav Erik Pettersson; [2023]
    Keywords : ;

    Abstract : The implementation of systems and methodologies for time series anomaly detection holds the potential of providing timely detection of faults and issues in a wide variety of technical systems. Ideally, these systems are able to identify deviations from the normal behavior of systems even before any problems manifest, thus enabling proactive maintenance. READ MORE

  4. 3. Exploring a unique pocket in Galectin-8N by the synthesis of D-galactoside-based benzimidazole inhibitors

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Sid Bartold; [2023]
    Keywords : organic chemistry; synthesis; gal; gal-8; gal-8N; galectin; galectin-8; galectin-8N; inhibitor; drug development; benzimidazole; galactoside; carbohydrate; carbohydrate chemistry; Suzuki-coupling; Chemistry;

    Abstract : Galectins are a family of glycan-binding proteins where galectin-8 is a part of the subgroup known as tandem-repeat type galectins. Galectin-8 is composed of two homologous CRDs, one N- and one C-terminal CRD. As it stands now, galectin-8N has been found to bind to a larger number of glycans than galectin-8C. READ MORE

  5. 4. Characterization of potato protein and its calcium binding capacity

    University essay from Lunds universitet/Beräkningskemi; Lunds universitet/Tillämpad biokemi

    Author : Signe König; Erika Thomson; [2023]
    Keywords : Patatin; Calcium; Food supplement; Calcium Assay; Alcalase; potato protein; Applied biochemistry; Biology and Life Sciences; Technology and Engineering;

    Abstract : Calcium is essential for the human body as it has functions in the nervous system, bones and formation of teeth. Deficiency in this important nutrient can be detrimental to health and cause life-long issues. Calcium can be found in various foods, like dairy products, but certain plant-based alternatives to milk needs to be fortified with calcium. READ MORE

  6. 5. Production, in vitro modification, and interaction analysis of a hydroxyproline-dependent protein

    University essay from Uppsala universitet/Biokemi

    Author : Milica Plavsic; [2023]
    Keywords : protein production optimisation; recombinant expression; bioreactor; prolyl hydroxylase; liquid chromatography mass spectrometry; microscale thermophoresis;

    Abstract : The development of a biologic protein involves different stages and becomes a highly complex process which can be costly and time consuming to scale up for industrial production. Therefore, optimization is a necessary part of the production process development to lower the production expenses. READ MORE