Essays about: "LC-MS MS"

Showing result 1 - 5 of 58 essays containing the words LC-MS MS.

  1. 1. Leveraging CNN for Automated Peak Picking in Untargeted Metabolomics without Parameter Dependencies

    University essay from Göteborgs universitet/Institutionen för data- och informationsteknik

    Author : Vivian Wang; Lidia Yalew; [2023-10-19]
    Keywords : Deep learning; Convolutional neural network; LC-MS; Peak Detection; Metabolomics; Faster R-CNN;

    Abstract : Metabolomics is a scientific discipline that involves the thorough analysis of small molecules, known as metabolites, found within a biological system. Furthermore, liquid chromatography-mass spectrometry (LC-MS) is a commonly used analytical technique in metabolomics for analysing biological samples due to its broad coverage of the measurable metabolome. READ MORE

  3. 2. Selected PFAS in the water treatment at the waste-to-energy plant in Umeå : Investigating concentration and composition of selected PFAS in different water treatment steps

    University essay from Umeå universitet/Institutionen för ekologi, miljö och geovetenskap

    Author : Amanda Carlund; [2023]
    Keywords : ;

    Abstract : The present study investigated the changes in concentration and composition of five selected PFAS substances in the water treatment at the waste-to-energy plant in Umeå. The five PFAS were PFHxA, PFHpA, PFOA, PFHxS and PFOS. As PFAS exists in a variety of consumer products, they will to some extent end up in waste incineration. READ MORE

  4. 3. Creating a High-Throughput Workflow for Automated Peptide Characterization using LC-MS

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Sara Forsberg; [2023]
    Keywords : High-throughput analysis; Impurity profiling; UHPLC-HRMS; Peptide characterization; Peptide descriptors; Analytical chemistry; Technology and Engineering;

    Abstract : In the early stage of a drug discovery project, there is a need for efficient methods that can analyse peptides in short time. This includes methods that confirm the peptide’s identity and estimates its relative purity in an efficient and reliable way. READ MORE

  5. 4. Exploratory study of ion pair liquid chromatography separation methods and sample preparation procedures – for quantification of amount 5’capped and uncapped mRNA

    University essay from Karlstads universitet/Institutionen för ingenjörs- och kemivetenskaper (from 2013)

    Author : Felicia Lindström; [2023]
    Keywords : ;

    Abstract : Using ion pair chromatography, separation and analysis of shorter mRNA fragments was possible. The aim of the study was to develop a separation method for quantitation of 5’capped versus uncapped mRNA. Cleavage of mRNA was performed by complementary probes and the enzyme RNase H which created shorter mRNA fragments containing the 5’ end. READ MORE

  6. 5. Remediation of per- and polyfluoroalkyl substances (PFAS) in contaminated water by sorption to pine- and spruce bark

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Rebecka Ayranci Dahlberg; [2023]
    Keywords : Per- and polyfluoroalkyl substances; sorption; pine bark; spruce bark; ultra-short-chain PFAS; short-and long-chain PFAS; elemental analysis; field-test;

    Abstract : PFAS are anthropogenic substances used in many different industrial operations and products because of their unique properties. Due to their negative impact on human health and environmental bioaccumulative characteristics different authorities have addressed the issue. In Sweden the limit is4 ng/L for four different PFAS in drinking water. READ MORE