Essays about: "Ligand bound structure"
Found 5 essays containing the words Ligand bound structure.
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1. Structural features underlying antigen presentation by the non-classical MHC class Ib molecule Qa-1b
University essay from KTH/ProteinvetenskapAbstract : Blockering av NKG2A receptorn på NK - och CD8+ T celler med en anti-NKG2A antikropp, medför en aktivering av cytolytisk aktivitet, och är en lovande immunkontrollpunkt i immunterapi mot cancer. Nyligen har en TCR-liknande antikropp, EXX1, som binder till liganden för NKG2A receptorn, Qa-1b - en icke-klassisk MHC klass Ib molekyl i möss -studerats i tumör modeller in vitro. READ MORE
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2. Characterisation of Potential Inhibitors of Calmodulin from Plasmodium falciparum
University essay from Linköpings universitet/Institutionen för fysik, kemi och biologiAbstract : Each year countless lives are affected and about half a million people die from malaria, a disease caused by parasites originating from the Plasmodium family. The most virulent species of the parasite is Plasmodium falciparum (P. falciparum). READ MORE
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3. Mutational engineering, growth selection, expression, purification and crystallization of ligand bound endo-beta-N-acetylglucosaminidase T (Endo-T) from Hypocrea jecorina
University essay from SLU/Dept. of Molecular Biology (until 131231)Abstract : Recently, one of the first fungal-expressed, deglycosylating, Endo-beta-N-acetylglucosaminidases was found in the extracellular medium of soft-rot ascomycete Hypocrea jecorina (a.k.a. Trichoderma reesei) belonging to glycoside hydrolase family 18 (GH18). READ MORE
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4. Structure-function studies of biomass degrading enzymes : crystallization of EndoT from Hypocrea jecorina and Cel5H from Saccharophagus degradans, and enzyme hharacterization of Cel5H
University essay from SLU/Dept. of Molecular Biology (until 131231)Abstract : The purpose of this project was to investigate the structure-function relationship of two carbohydrate active enzymes, Endo-N-acetyl-β-(D)-glucosaminidase (EndoT) from Hypocrea jecorina and Cel5H from Saccharophagus degradans.The enzyme Endo-T from H. READ MORE
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5. Design, Synthesis and Biological testing of Novel ligands for Ghrelin Receptor
University essay from Institutionen för vård och naturAbstract : Abstract G-protein coupled receptors (GPCRs) are having the high medical importance since almost half of the medicinal drugs are designed as modulators of receptor molecules. Crystal structure or NMR structures of GPCRs are very difficult to determine because all GPCRs are typically bound to the cell membrane and thus their molecular activation mechanism is still unclear. READ MORE