Essays about: "Long non RNA"

Showing result 1 - 5 of 18 essays containing the words Long non RNA.

  1. 1. Non-coding RNAs as therapeutic agents : The future of therapy

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Hederoth Gustaf; Lyngå Olivia; Rudqvist Olivia; Jeppsson Rebecka; Hogolof Saida; Svanberg Sara; Kauppinen Veera; [2022]
    Keywords : Non-coding RNA; Oligonucleotide therapeutics;

    Abstract : Non-coding RNA (ncRNA) therapeutics are based on short oligonucleotides, both naturally occurring and artificial, which target RNA in a site-specific way to modulate gene expression. As of today, 12 synthetically produced ncRNA-based drugs are available on the market in the US and Europe, and there is a possibility of more to be approved in the near future. READ MORE

  3. 2. Comprehensive Analysis of lncRNA and circRNA Mediated ceRNA network in Psoriasis

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Saima Imran; [2022]
    Keywords : ;

    Abstract : Evidence is accumulating that noncoding RNAs and circRNA are involved in psoriasis; however, the competing endogenous RNA (ceRNA) mediated regulatory mechanisms in psoriasis are rarely reported. The research study aimed to comprehensively investigate the differences in the expression levels of circular RNA (circRNA), long non-coding RNA (lncRNA), microRNA (miRNA/miR), and mRNA in psoriasis. READ MORE

  4. 3. Evaluation of the Two-tailed RT-qPCR method with the application of manual vs robotic extraction of miRNA

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Lia Rozenberg; [2022]
    Keywords : ;

    Abstract : Sepsis is aggressive and severe inflammatory body response to an infection and is considered to be one of the most common death causes in patients. The current diagnosis of sepsis is not fast enough to help those who get sepsis, due to its fast progression. The current golden standard for sepsis diagnosis is blood culturing. READ MORE

  5. 4. 3′-end fluorescence labelling of long RNAs using terminal deoxynucleotidyl transferase

    University essay from Lunds universitet/Kemiska institutionen

    Author : Johannes Lidberg; [2022]
    Keywords : Physical biochemistry; Fluorescence; In vitro transcription; RNA; Terminal deoxynucleotidyl transferase; Nucleobase analogue; Chemistry;

    Abstract : Through recent years, RNA has rapidly gone from mainly being known as a passive information-carrying molecule within the central dogma of molecular biology to becoming the active ingredient in multiple therapeutics, such as in vaccines and potential drugs against cancer. However, one of the main challenges with RNA as a therapeutic is efficient delivery to cells. READ MORE

  6. 5. Extraction of miR-223 from human blood plasma and quantification using the two-tailed RT-qPCR and absolute quantification

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Lucija Marinkovic; [2021]
    Keywords : ;

    Abstract : Sepsis is a very dangerous and life-threatening disease that develops when the body’s reaction to infection causes damage to the body’s tissues and organs. It is difficult to diagnose it and it develops fast leading to a high mortality rate. READ MORE