Essays about: "M protein"

Showing result 1 - 5 of 81 essays containing the words M protein.

  1. 1. Integrating web data miningand machine learningalgorithms to predict progression free survival and overall survival in multiple myeloma patients

    University essay from Uppsala universitet/Institutionen för informationsteknologi

    Author : Yijie Zhou; [2023]
    Keywords : ;

    Abstract : Multiple myeloma patients have highly variable progression free survival and overall survivalranging from a few weeks to more than 5 years. Stratification of these patients can help toidentify high risk patients i-e patients with short-term progression free survival and overallsurvival. READ MORE

  3. 2. Combining doxorubicin and gemcitabine with targeted drugs as a treatment option for high-risk neuroblastoma

    University essay from KTH/Proteinvetenskap

    Author : Alexandra Johannesson; [2023]
    Keywords : neuroblastoma; doxorubicin; gemcitabine; targeted drugs; ATM; neuroblastom; doxorubicin; gemcitabin; målinriktade läkemedel; ATM;

    Abstract : Neuroblastom är en barncancer som uppstår ur det sympatiska nervsystemet och drabbar omkring 15 barn i Sverige varje år. Högriskvarianten är associerad med mycket hög dödlighet och risk för återfall, vilket tros ha att göra med att tumörernas ovanligt heterogena sammansättning tillåter resistenta subpopulationer att motstå konventionella behandlingsmetoder. READ MORE

  4. 3. Concentration of Proteins and Decrease of Salt Content in a Hydrolyzed Fermentation Broth Using Membrane Filtration

    University essay from Lunds universitet/Kemiteknik (CI)

    Author : Linnea Sjökvist; [2023]
    Keywords : Membrane filtration; ultrafiltration; PHA; polyhydroxyalkanoates; chemical engineering; Technology and Engineering;

    Abstract : Membrane filtration was used to concentrate proteins and decrease the salt concentration in a hydrolyzed fermentation broth. The broth was a by-product from the bacterial production and extraction of polyhydroxyalkanoates (PHA), that can be used to produce biobased plastics. READ MORE

  5. 4. Exploring a unique pocket in Galectin-8N by the synthesis of D-galactoside-based benzimidazole inhibitors

    University essay from Lunds universitet/Centrum för analys och syntes

    Author : Sid Bartold; [2023]
    Keywords : organic chemistry; synthesis; gal; gal-8; gal-8N; galectin; galectin-8; galectin-8N; inhibitor; drug development; benzimidazole; galactoside; carbohydrate; carbohydrate chemistry; Suzuki-coupling; Chemistry;

    Abstract : Galectins are a family of glycan-binding proteins where galectin-8 is a part of the subgroup known as tandem-repeat type galectins. Galectin-8 is composed of two homologous CRDs, one N- and one C-terminal CRD. As it stands now, galectin-8N has been found to bind to a larger number of glycans than galectin-8C. READ MORE

  6. 5. Predicting tumour growth-driving interactions from transcriptomic data using machine learning

    University essay from Uppsala universitet/Neuroonkologi och neurodegeneration

    Author : Mathilda Stigenberg; [2023]
    Keywords : cancer; immunology; cell-cell interactions; deep learning; variational autoencoder; supervised variational autoencoder; tumour microenvironment; single-cell RNA sequencing; spatial transcriptomics; breast cancer; machine learning;

    Abstract : The mortality rate is high for cancer patients and treatments are only efficient in a fraction of patients. To be able to cure more patients, new treatments need to be invented. Immunotherapy activates the immune system to fight against cancer and one treatment targets immune checkpoints. READ MORE