Essays about: "MHC 1"

Showing result 1 - 5 of 9 essays containing the words MHC 1.

  1. 1. Structural features underlying antigen presentation by the non-classical MHC class Ib molecule Qa-1b

    University essay from KTH/Proteinvetenskap

    Author : Lejla AI-Tamimi; [2022]
    Keywords : immune checkpoint; NKG2A; MHC class Ib; Qdm; antibody; crystal structure;

    Abstract : Blockering av NKG2A receptorn på NK - och CD8+ T celler med en anti-NKG2A antikropp, medför en aktivering av cytolytisk aktivitet, och är en lovande immunkontrollpunkt i immunterapi mot cancer. Nyligen har en TCR-liknande antikropp, EXX1, som binder till liganden för NKG2A receptorn, Qa-1b - en icke-klassisk MHC klass Ib molekyl i möss -studerats i tumör modeller in vitro. READ MORE

  3. 2. Physiological characteristics of sodium lactate infusion during resistance exercise

    University essay from Gymnastik- och idrottshögskolan, GIH/Institutionen för idrotts- och hälsovetenskap

    Author : Sebastian Danielsson; [2019]
    Keywords : sodium lactate; sodium lactate infusion; infusion; resistance exercise; knee-extensor; vastus lateralis; metabolic effects; hematological effects; plasma lactate; muscle lactate; muscle content of lactate; MHC; fiber type; blood pH; muscle pH; blood lactate; blood sodium; blood potassium; blood glucose; hemoglobin; in vivo; randomized; cross-over;

    Abstract : Previous studies that utilized sodium lactate infusion did not use resistance exercise protocol or analyzed muscle biopsies, or performed sex specific analysis. Aim: We initiated a project where resistance exercise was performed with low and high levels of lactate, acquired by venous lactate infusion where the specific aim of this study was to investigate and chart the physiological characteristics of sodium lactate infusion during a bout of resistance exercise on whole group level and sexes separated Method: A randomized, placebo controlled, cross-over design was implemented where male (n = 8) and female (n = 8) subjects accustomed to resistance exercise visited the laboratory three times for preliminary testing and training familiarization. READ MORE

  4. 3. Canine transmissible venereal tumour

    University essay from SLU/Dept. of Anatomy, Physiology and Biochemistry

    Author : Oskar Eriksson; [2017]
    Keywords : CTVT; smittsam könstumör; hund; tumör;

    Abstract : Canine Transmissible Venereal Tumour (CTVT) är en unik smittsam tumörsjukdom. Likt en parasit är den naturligt överförbar mellan individer inom familjen Canidae via transplantation av levande tumörceller, framför allt genom parning. READ MORE

  5. 4. The molecular background of equine sarcoids

    University essay from SLU/Dept. of Animal Breeding and Genetics

    Author : Katarina Hörnaeus; [2013]
    Keywords : Equine sarcoids; genetic background; Major Histocompatibility Complex MHC ; Bovine papillomavirus; microsatellites;

    Abstract : Equine sarcoids (ES) are the most common skin tumors in equids all over the world. No universal treatment is yet available and the aetiology of the disease is not yet fully understood. Though, it is believed to be a multifactorial disease in which both genetic and infectious factors have been implicated. READ MORE

  6. 5. Analysis of Map3k-dependent molecular mechanisms regulating signaling in iNKT and B cells

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Saba Anwar; [2013]
    Keywords : Biology and Life Sciences;

    Abstract : Abstract Our immune system consists of two types of lymphocytes; B lymphocytes which produce antibodies in response to an antigen, and T lymphocytes which differentiate into particular effector T lymphocytes such as a cytotoxic, helper or regulatory T cell in response to an antigen. Type 1 invariant natural killer T cells (iNKT cells) are a unique population of T cells whose phenotypical, developmental and functional characteristics differ from conventional T cells (Novak and Lehuen, 2011). READ MORE