Essays about: "ML cells"

Showing result 1 - 5 of 79 essays containing the words ML cells.

  1. 1. OPTIMIZATION OF CLONE SELECTION PLATFORM FOR PRODUCTION OF RECOMBINANT PROTEINS

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Basel Yousef; [2024]
    Keywords : ;

    Abstract : Background  Biologics are type of proteins that can be produced by expression in a foreign host for medical healthcare applications in humans. Monoclonal antibodies (mAbs) are type of biologics that are designed to specifically bind to one target, with a purpose to inhibit a certain molecule that could be associated with a disease process. READ MORE

  3. 2. Studies of broad-spectrum inhibitors against main protease of SARS-CoV-2 and other Coronaviruses

    University essay from Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Author : Alexandra Stanciu; [2023]
    Keywords : human coronavirus 229E; SARS-CoV-2; main protease; nirmatrelvir; GC-376; compound 19;

    Abstract : Coronaviruses have caused three large outbreaks in the past century. The most recent one, also still ongoing, is represented by the SARS-CoV-2/Covid-19 pandemic. Efforts have been taken to develop efficient vaccines and antivirals and one of the major virus-based targets in drug development is represented by the main protease of these viruses. READ MORE

  4. 3. Fibroblasttillväxtfaktor-23 (FGF-23) – en möjlig biomarkör för osteoartrit hos katt?

    University essay from SLU/Dept. of Clinical Sciences

    Author : Pernilla Hägg; [2023]
    Keywords : artros; biomarkör; FGF-23; katt; osteoartrit;

    Abstract : Osteoartrit är en kronisk obotlig ledsjukdom som är vanlig hos katt. Trots att osteoartrit är associerad med smärta kan sjukdomen hos katt vara svår att diagnosticera. READ MORE

  5. 4. Development of specific host cell protein assays

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Anna Ivert Nordén; [2023]
    Keywords : Gyrolab; Immunoassay; HCP;

    Abstract : The manufacturing and the development of biotherapeutic drugs involves the expression of biotherapeutic proteins in a host cell expression system followed by a purification process. Bioanalytical methods to measure impurities such as host cell proteins (HCPs) are needed to obtain a robust process and a safe drug according to regulatory requirements. READ MORE

  6. 5. Recombinant expression and purification of sugar beet Phytoglobins in Escherichia Coli BL21 (DE3) including metabolic engineering of the heme biosynthesis

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Pennie Lindblom; Olivia Geel; [2023]
    Keywords : Phytoglobin; Heme; δ-ALA; qPCR; SDS-PAGE; Bacterial cultivation; Escherichia coli; BvPgb1.2; ÄKTA; Applied biochemistry; Biology and Life Sciences;

    Abstract : The protein hemoglobin (Hb) is vital for us humans to ensure enough oxygen replacement in the body. Hb-resembling proteins also exist in plants, these are called phytoglobins (Pgbs). Pgbs are very interesting since they can play a considerable role in the development of blood substitutes and iron supplements for human use. READ MORE