Essays about: "MYCN"

Showing result 1 - 5 of 9 essays containing the word MYCN.

  1. 1. Quantification of the expression of hsa-mir-34c-5p in neuroblastoma cells

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Lorena Trissl; [2022]
    Keywords : ;

    Abstract : Neuroblastomas are the most common extra-cranial abnormal growths in immature nerve tissue within the sympathetic nervous system, in children ages 0-5. It is a heterogeneous malignancy, often emerging in and around adrenal glands, caused by rapid growth and division of nerve cells. READ MORE

  3. 2. The Effects of MYCN amplification and 11q : Deletion on the Expression Level of  hsa-miR-34b-3p in Neuroblastoma

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Adnan Moalim; [2022]
    Keywords : ;

    Abstract : Neuroblastoma is a form of embryonal neuroendocrine tumor that arises from neural crest progenitor cells, which can differentiate into multiple cell types. It is caused by genetic abnormalities such as MYCN oncogene amplification and 11q deletion, both of which can deregulate neuroblastoma suppressor genes located on chromosome 11q. READ MORE

  4. 3. Targeting DNA repair mechanisms in aggresive neuroblastoma

    University essay from Högskolan i Skövde/Institutionen för hälsovetenskaper

    Author : Rafael Ruiz Alarcón; [2021]
    Keywords : ;

    Abstract : Neuroblastoma is a tumour derived from cells of the nervous system and is the most common solid tumour in childhood. MYCN amplified and 11q-deleted neuroblastoma, two high-risk neuroblastoma were investigated in this study. READ MORE

  5. 4. Isoform 2 of DLG2 gene as a possible candidate tumour suppressor of neuroblastoma

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Paula Camargo Romera; [2021]
    Keywords : ;

    Abstract : Neuroblastoma (NB) is the most frequent extracranial solid tumour in childhood. The clinical diagnosis of NB is difficult due to the age of the patient and the vague appearance of the symptoms. Moreover, there are two groups of aggressive NBs, one with MYCN amplification and the other with an 11q deletion. READ MORE

  6. 5. Interactions between Rho-ROCK signaling and the tumor microenvironment in neuroblastoma

    University essay from Uppsala universitet/Mikrobiologi och immunologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Adena Pepich; [2021]
    Keywords : cancer and oncology; pediatric cancer; neuroblastoma; rho ROCK signaling; rho-associated kinases; tumor microenvironment; cytotoxic T cells; neuroblastom; pediatrik onkologi; rho-kinaser;

    Abstract : Neuroblastoma is a childhood cancer of the peripheral sympathetic nervous system, emerging from cells of the neural crest. In Sweden, neuroblastoma accounts for 20 cases out of all, 300-350, pediatric cancer cases each year (Barncancerfonden 2019, Turup on behalf of Cancer Centrum 2019). READ MORE