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Found 4 essays matching the above criteria.

  1. 1. Identification and network analysis of candidate microRNA biomarkers in neuroblastoma : A meta-analysis

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Andreas Svensson; [2022]
    Keywords : ;

    Abstract : Neuroblastoma constitutes roughly 8% of all childhood cancers where 95% of all neuroblastoma cases occur before the age of 10. The survival rate of infants and young children is very poor, which alone contributes to research novel biomarkers for classification methods, improved diagnosis and better anti-tumor therapies. READ MORE

  3. 2. Role of Aurora kinase in Medulloblastoma development with correlation to MYCN activity

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Rashmi Chowath; [2015]
    Keywords : brain tumor; N-Myc; primary cilium; aurora kinase;

    Abstract : Brain tumors are abnormal tissue masses found, either malignant or benign in nature. Medulloblastoma is a brain tumor subtype found to arise in the hind region of the brain, which is highly malignant and has poor long term prospects in general. READ MORE

  4. 3. Identification of MYCN and SOX9 target genes and a study of drug treatment effects in medulloblastoma

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Tiolina Östergren; [2015]
    Keywords : Medulloblastoma; MYCN; MYC; SOX9; HES1; ChIP; recurrence;

    Abstract : Medulloblastoma (MB) is the most common malignant brain tumor affecting children. The transcription factors MYCN and SOX9 are associated with initiation, maintenance and recurrence of MB and are also connected to more aggressive tumors. READ MORE

  5. 4. Radiobiological optimization including consideration of secondary cancer risk A treatment modality comparison study for pediatric medulloblastoma

    University essay from Lunds universitet/Sjukhusfysikerutbildningen

    Author : Patrik Brodin; [2010]
    Keywords : Strålterapi; Medicine and Health Sciences;

    Abstract : Purpose: To estimate and compare normal tissue toxicity and secondary cancer (SC) risks from 3D conformal radiotherapy (3D CRT), arc radiotherapy (ART) and intensity modulated proton therapy (IMPT) for treatment of pediatric medulloblastoma (MB). The purpose was also to investigate the possibility of optimizing radiotherapy treatment with the aim of reducing normal tissue toxicity as well as the risk of SC. READ MORE