Essays about: "Methylation"

Showing result 1 - 5 of 55 essays containing the word Methylation.

1. 1. Impact of BPA, BPF and Mixture N1 on DNA-Methylation of GRIN2B and NR3C1 during human neuroprogenitor cell differentiation

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Fysiologi och miljötoxikologi

   Author : Franziska Sophie Richter; [2023]
   Keywords : Epigenetics; Endocrine disrupting chemicals; DNA methylation; EDCs; Mixture effects; BPA; BPF; Mixture N1;

   Abstract : Endocrine disrupting chemicals (EDCs) are ubiquitous and their adverse impact on nature, wildlife and humans is extensively researched. We are constantly exposed to EDCs, such as the widespread and extensively researched Bisphenol A, as well as its substitute Bisphenol F, which is coming into wider use, even though it is much less is researched and limited information is available about its endocrine effects. READ MORE

3. 2. Identification of epigenetic biomarkers associated with the development of diabetic kidney disease in individuals with type 2 diabetes: a nested cohort study

   University essay from Lunds universitet/Socialmedicin och global hälsa

   Author : Marian Paiva Marchiori; [2023]
   Keywords : Medicine and Health Sciences;

   Abstract : Introduction. Type 2 diabetes (T2D) is the most common type of diabetes, and it can cause complications such as diabetic kidney disease (DKD), the main cause of end-stage renal disease worldwide. There is an urgent need to develop new biomarkers that would improve DKD’s risk prediction in patients with T2D. READ MORE

4. 3. Newly inundated forest landscapes - hotspots for mercury in water and benthic fauna

   University essay from SLU/Dept. of Aquatic Sciences and Assessment

   Author : Kirstine Evald Andersson; [2023]
   Keywords : Wetland restoration; Inundation; Mercury cycling; Beaver impoundments; Aquatic biogeochemis-try;

   Abstract : Mercury (Hg) is a widespread contaminant in high-latitude aquatic ecosystems, where it can undergo microbial transfor-mation into toxic methylmercury (MeHg). Due to its chemical properties, MeHg tends to accumulate in the aquatic food chain and will eventually end up in predatory species at the top of the terrestrial food web. READ MORE

5. 4. Non-coding RNAs as therapeutic agents : The future of therapy

   University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

   Author : Hederoth Gustaf; Lyngå Olivia; Rudqvist Olivia; Jeppsson Rebecka; Hogolof Saida; Svanberg Sara; Kauppinen Veera; [2022]
   Keywords : Non-coding RNA; Oligonucleotide therapeutics;

   Abstract : Non-coding RNA (ncRNA) therapeutics are based on short oligonucleotides, both naturally occurring and artificial, which target RNA in a site-specific way to modulate gene expression. As of today, 12 synthetically produced ncRNA-based drugs are available on the market in the US and Europe, and there is a possibility of more to be approved in the near future. READ MORE

6. 5. Evaluation and implementation of quality control parameters for genome-wide DNA methylome sequencing

   University essay from Högskolan i Skövde/Institutionen för biovetenskap

   Author : Sara Ekberg; [2022]
   Keywords : ;

   Abstract : Epigenomics is the study of modifications to the genetic material without changes to the DNA sequence, one such modification is methylation of nucleotides. DNA methylation is associated with gene regulation and is studied in a variety of fields such as cancer and ageing. READ MORE