Essays about: "Model peptides"

Showing result 1 - 5 of 19 essays containing the words Model peptides.

  1. 1. Benchmarking Machine Learning Methods for Peptide Activity Predictions

    University essay from Göteborgs universitet/Institutionen för data- och informationsteknik

    Author : Boel Knutson; Lida Meskini Moudi; [2022-10-14]
    Keywords : Drug discovery; peptide; classification; molecular representation; Z-scales; pseudo amino acid composition; one-hot representation; random forests; support vector machines;

    Abstract : One of the main challenges in the drug discovery process is to find a suitable compound for further analysis. The compound must affect the target relevant for the specific disease, while at the same time have desired properties to make it a safe and efficient drug candidate. READ MORE

  2. 2. Optimal peptide quantification via machine learning enhanced fragment ion ranking in DIA-MS proteomics

    University essay from Lunds universitet/Examensarbeten i bioinformatik

    Author : Lina Lu; [2022]
    Keywords : Biology and Life Sciences;

    Abstract : In a standard mass spectrometry workflow, acquired mass spectra are searched against a library of peptides to extract peptide spectra matches (PSMs). Peptides are normally quantified by aggregating the intensities of fragment ions extracted from MS/MS spectra. READ MORE

  3. 3. An investigation of the interactions between clay nanoplatelets in the presence of monovalent and divalent salts, as well as cationic peptides utilising atomistic molecular dynamics

    University essay from Lunds universitet/Kemiska institutionen

    Author : Mona Koder Hamid; [2020]
    Keywords : clay; molecular dynamics simulations; physical chemistry; fysikalisk kemi; theoretical chemistry; teoretisk kemi; Chemistry;

    Abstract : Clays are negatively charged nanoplatelets with a layered silicate structure. It has been observed from small angle X-ray scattering measurements, and coarse-grained molecular dynamics simulations (CG-MD) that clay nanoplatelets are able to form stacks, known as tactoids, in the presence of divalent or multivalent counterions [8, 5]. READ MORE

  4. 4. Total proteolysis in bovine raw bulk milk of Northern Sweden

    University essay from SLU/Department of Molecular Sciences

    Author : Elina Toss Ekmyr; [2020]
    Keywords : total proteolysis; plasmin; SDS PAGE; total bacteria count; somatic cell counts;

    Abstract : Proteases are enzymes that catalyze protein breakdown. The major indigenous protease is plasmin, that together with proteases originating from somatic cells and bacteria, accounts for most of the proteolytic activity in bovine milk. In many dairy products, the key characteristics depends on the concentration and composition of the milk proteins. READ MORE

  5. 5. Aqueous self-assembly behaviour alteration derived from primary structure changes of model peptides

    University essay from Lunds universitet/Kemiska institutionen

    Author : Marcus Bäcklund; [2020]
    Keywords : Model peptides; self-assembly; SAXS; FTIR; CD; physical chemistry; fysikalisk kemi; Chemistry;

    Abstract : Understanding of the self-assembly behaviour of peptides is of great interest within several different areas such as neurodegenerative diseases, biotechnology, and peptide pharmaceuticals. In this work we have compared the impact on the self-assembly behaviour derived from systematic changes of the primary structure of A8K, where A denotes alanine and K lysine. READ MORE