Essays about: "Mutation analysis"
Showing result 1 - 5 of 73 essays containing the words Mutation analysis.
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1. Estimating Variant Intolerance for Genes of Cattle
University essay from SLU/Dept. of Animal Breeding and GeneticsAbstract : Cattle play a crucial role in providing nutrition and economic stability worldwide. Threats to their health, particularly infectious diseases, and genetic mutations, can have profound implications for both animal and human livelihoods. READ MORE
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2. Analysis of relatedness and genetic diversity in Swedish sheep breeds using medium density (50K) SNP data
University essay from SLU/Dept. of Animal Breeding and GeneticsAbstract : The local Swedish sheep breeds belong to a group of sheep breeds known as North European short-tailed sheep breeds. Evaluation of genetic diversity, relatedness, and population structure of local breeds offers crucial metrics to prevent inbreeding depression, genetic erosion, and crossbreeding between locally adapted and exotic sheep breeds since these occurrences can have detrimental effects and ultimately lead to extinction. READ MORE
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3. Molecular characterization of vascular malformations using single-cell RNA sequencing and immunohistological analysis
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : CCM is a human disease in which vascular malformations develop in the central nervous system, predominantly in the brain. The malformations which can measure up to several centimeters in size are dilated and leaky vessels, with unstable cellular junctions and thin vessel walls. READ MORE
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4. Evaluating targeted combination therapies in EGFR wild-type non-small-cell lung cancer using mass spectrometry-based proteomics
University essay from Lunds universitet/Institutionen för immunteknologiAbstract : Survival for non-small cell lung cancer (NSCLC) patients has been significantly improved by epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with EGFR mutations. However, certain subpopulations of NSCLC patients with EGFR wild-type (wt) status have been shown to also respond to EGFR-TKIs. READ MORE
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5. Transcriptional basis of Huntington’s Disease: Gene expression analysis indicate increased immune responses in the brain and mitochondrial dysfunction in adipose tissues of HD model mouse
University essay from KTH/ProteinvetenskapAbstract : Huntingtons sjukdom (HD) är ett neurodegenerativt tillstånd som orsakas av mutationer i huntingtin gen (Htt), och resulterar till upprepade glutamin (polyQ) i Htt-proteinet. Muterad Htt kan inte vika sig ordentligt och börjar därför aggregera i celler. READ MORE