Essays about: "NALP3"

Found 1 essay containing the word NALP3.

  1. 1. Mutations E688K and G569R within the NALP3 gene, associated with development of hereditary auto inflammatory disorders   

    University essay from Institutionen för vård och natur

    Author : Alija Fetah; [2009]
    Keywords : Mutations; autoimmune disorders;

    Abstract : Different mutations within the NALP3 gene are thought to be associated with development of several types of hereditary auto inflammatory disorders such as neonatal onset multisystem inflammatory disorder (NOMID) and muckle-wells syndrome (MWS). In this work two separate mutations E688K and G569R were supposed to be constructed by site-directed mutagenesis in the cloned wild type NALP3 genes and further expressed in bacterial and mammalian host cells for functional studies in protein -protein interaction models. READ MORE