Essays about: "NLRP3"

Showing result 1 - 5 of 14 essays containing the word NLRP3.

  1. 1. Upregulation of CLIC1 gene in THP1 cells stimulated by lipopolysaccharides

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Karldiony Roskvist; [2021]
    Keywords : ;

    Abstract : The NLRP3 inflammasome is a multiprotein complex that controls caspase-1 activation and the development of the pro-inflammatory cytokines IL-1 and IL-18, as well as pyroptosis. The NLRP3 inflammasome in murine macrophages is normally triggered by pathogen-associated molecular patterns as well as a variety of structurally unrelated stimuli. READ MORE

  2. 2. Expression of the chloride channel CLCC1 is downregulated after 24 hours in LPS-primed THP-1 monocyte-like cell line

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Omar Babena; [2021]
    Keywords : ;

    Abstract : Inflammation is the body's response to infection or injury and is mediated by the innate immune system. The NLRP3 inflammasome is a multi-protein complex that is a major contributor to many inflammatory disorders. Emerging evidence suggests the involvement of the Endoplasmic reticulum stress with the NLRP3 inflammasome. READ MORE

  3. 3. Evaluating the gene expression levels of NFkB2 and RELA after LPS priming

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Armand Stoe; [2021]
    Keywords : ;

    Abstract : The regulatory process of inflammation is very important for the well-being of an organism. Disruption of this process can lead to very dire consequences. The innate immune system is responsible in activating the inflammatory response. As a result of an inflammatory response, inflammasome complexes such as NLRP3 can activate. READ MORE

  4. 4. Protein-protein interactions with and within the NLRP3 inflammasome : Evidence from STRING and literature studies

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Ralph Monte; [2020]
    Keywords : ;

    Abstract : Inflammasomes are multiprotein complexes that play a role in the innate immune system. One inflammasome is the NLRP3 inflammasome, which can be activated and primed by different stimuli that bind to pattern recognition receptors (PRRs). READ MORE

  5. 5. microRNA-200 Family Expression Level Changes in Stimulated THP-1 Cells Following NLRP3 Inflammasome Activation

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Kristina Backlund; [2020]
    Keywords : ;

    Abstract : Innate immunity is the immune systems rapid responses to infection after being attacked by a pathogen. Inflammatory responses are activated by the detection of pathogen-associated molecular patterns and danger-associated molecular patterns through pattern recognition receptors on inflammatory cells. READ MORE