Essays about: "NLRP3"

Showing result 11 - 15 of 18 essays containing the word NLRP3.

  1. 11. Activation of NLRP3 inflammasome leads to the differential secretion of interleukins 1*/18 possibly linked to pyroptosis in THP-1 cells

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Jana Damiani; [2020]
    Keywords : ;

    Abstract : Organisms are constantly exposed to microorganisms, some of which can cause disease, and yet, sickness only rarely occurs. Upon infection, the immune system is mobilized to eliminate the threat and re-establish homeostasis. READ MORE

  2. 12. Inflammasome : Investigating the effect of NEK7 in the activation of the NLRP3 Inflammasome

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Cosmas Adindu Uzowuru; [2020]
    Keywords : NLRP3 inflammasome; NEK7 protein; THP-1; Prime; activate; differentiate; stimulate; cytokines; Interleukin-1 Beta; Interleukin-18;

    Abstract : Inflammation is a biological defence mechanism applied by living organisms against foreign invaders. In the response to DAMPs and PAMPs, organisms use inflammatory multi-protein complexes to fight the attackers. The most studied inflammasome proteins are NLRP3, ASC and Caspase-1. READ MORE

  3. 13. miR-34 expression levels in relation to NLRP3 inflammasome activation in THP1-ASC-GFP cells : Pilot study

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Alyssa Smith; [2020]
    Keywords : ;

    Abstract : Inflammation is the body’s innate immune system responding to harmful stimuli. The body reacts to this stimuli by forming and activating inflammasomes. Inflammasome protein activation plays major roles seen in metabolic and autoimmune disorders, showing the importance of comprehending the processes involved. READ MORE

  4. 14. BABAM1 regulation of NLRP3 inflammasome in THP-1 monocyte-like cell lines

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Musa Marrah; [2020]
    Keywords : ;

    Abstract : The nucleotide-binding oligomerization domain–like receptor family pyrin domain containing 3 (NLRP3) inflammasome is a group of multi-protein complex that mediates immune responses through the production of biologically active IL-1β and IL-18. Dysregulation of NLRP3 inflammasome has been linked to various diseases associated with infection, inflammation, and cancer. READ MORE

  5. 15. Construction of a fusion protein for anchoring the inflammatory receptor NLRP3 to the cell membrane

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Rebecca Ling; [2019]
    Keywords : NLRP3 inflammasome; Overlap PCR; Fusion Protein; LPI™ technology;

    Abstract : The innate immune system are a cooperation of many components – receptors being one of them. Both membrane-bound and cytosolic receptors play a large role in the defence system against pathogens and danger. READ MORE