Essays about: "Nestin"

Found 5 essays containing the word Nestin.

  1. 1. Differential Thyroid Hormone Signaling in Human Astrocytes and Microglia

    University essay from Örebro universitet/Institutionen för naturvetenskap och teknik

    Author : Renée Levisson; [2021]
    Keywords : Thyroid hormones; Signaling; Astrocytes; Microglia;

    Abstract : Thyroid hormones (THs) play a fundamental role in brain function during development and adulthood. THs are essential regulators of neurogenesis, cell maturation and migration as well myelination and synaptogenesis. READ MORE

  3. 2. Effects of Different Laminins on Human Neural Progenitor Cells Cultured in 3D Electrospun Fibers

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Karl Vesterlund; [2019]
    Keywords : two-dimensional; three-dimensional; Alamar Blue; cell culture; drug development; extra-cellular matrix; electrospinning; immunocytochemistry; laminin; polycaprolactone; polymerase chain reaction; western blot; applied biochemistry; tillämpad biokemi; Technology and Engineering; Biology and Life Sciences;

    Abstract : A low success rate of drug candidates in clinical trials, and especially in brain research, motivates development of better screening models. Hence, in neuroscience and many other fields of Life Science, development of more physiological relevant experimental cell-based models is motivated. READ MORE

  4. 3. CRISPR/Cas9 gene-editing in an in vitro model of a familial form of ALS

    University essay from Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Author : Fredrik Nilsson; [2018]
    Keywords : ALS; SOD1; Amyotrophic lateral sclerosis; superoxide dismutase; CRISPR Cas9; sgRNA; stem cell; lentivirus; qPCR; FOXG1; nestin; immunocytochemistry; differentiation; forebrain neural progenitor; Applied Biochemistry; Biology and Life Sciences;

    Abstract : Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease characterized by the degeneration and death of both upper and lower motor neurons for which there is no cure currently available. The degeneration of motor neurons leads to the inability to carry out voluntary movement and death usually occurs 3-5 years after disease onset by respiratory failure. READ MORE

  5. 4. Green and red fluorescent protein tagging of endogenous proteins in glioblastoma using the CRISPR (clustered regularly interspaced short palindromic repeats)-Cas9 system

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Jenny Lindvall; [2016]
    Keywords : Glioblastoma; Cancer stem cells; CRISPR Cas9; Nestin; GFAP; GFP; RFP;

    Abstract : Glioblastoma multiforme is the most malignant primary brain tumor that affects adults, recognized by the World Health Organization as an aggressive grade IV astrocytoma. Patients diagnosed with this type of tumor are left with a poor prognosis even with the most advanced treatment available. READ MORE

  6. 5. Studies on neurogenesis in the adult human brain

    University essay from Institutionen för livsvetenskaper

    Author : Annika Andersson; [2010]
    Keywords : Neurogenesis; subgranular zone; adult human DG; Ki67;

    Abstract : Many studies on neurogenesis in adult dentate gyrus (DG) have been performed on rodents and other mammalian species, but only a few on adult human DG.  This study is focusing on neurogenesis in adult human DG. To characterize the birth of cells in DG, the expression of the cell proliferation marker Ki67 was examined using immunohistochemistry. READ MORE