Essays about: "Neurodegenerativa sjukdomar"

Showing result 1 - 5 of 20 essays containing the words Neurodegenerativa sjukdomar.

  1. 1. Chromatin accessibility analysis of spaceflight mouse brains using ArchR

    University essay from KTH/Genteknologi

    Author : Raphaël Mauron; [2023]
    Keywords : Single nuclei ATAC-sequencing; Space Biology; DNA Chromatin accessibility; Neurodegenerative; ArchR; ATAC-sekvensering av enskilda kärnor; rymdbiologi; tillgänglighet av DNA kromatin ; neurodegenerativa sjukdomar; ArchR;

    Abstract : Mänsklig utforskning av månen och Mars innebär stora utmaningar för människans fysiologi och hälsa på grund av de unika miljöfaktorer som följer av långvariga rymduppdrag. Rymdbiologiska experiment har blivit ett viktigt verktyg för att studera effekterna som mikrogravitation och rymdstrålning har på levande organismer, i syfte att förstå och minska dessa utmaningar. READ MORE

  3. 2. Effect of DNAJB6 on α-synuclein amyloid fibril aggregation and dis-aggregation

    University essay from Lunds universitet/Biofysikalisk kemi

    Author : Josef Getachew; [2023]
    Keywords : α-synuclein; alpha-synuclein; chaperones; DNAJB6; the unhappy chaperone; parkinsons disease; biophysical chemistry; biochemistry; Biology and Life Sciences; Chemistry; Technology and Engineering;

    Abstract : Amyloid proteins are a group of proteins with the ability to form large fibrillar aggregates, identifiable by their cross-β core structure. These aggregates are linked to several different neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease and due to the growing rate of people diagnosed, there is a need to combat these diseases. READ MORE

  4. 3. Transcriptional basis of Huntington’s Disease: Gene expression analysis indicate increased immune responses in the brain and mitochondrial dysfunction in adipose tissues of HD model mouse

    University essay from KTH/Proteinvetenskap

    Author : Intisar Salim; [2023]
    Keywords : Huntington’s Disease; mRNA-seq; tissue specific gene expression; cerebrospinal fluid; biomarker; Huntingtons sjukdom; mRNA-seq; vävnadsspecifik genexpression; cerebrospinalvätska; biomarkör;

    Abstract : Huntingtons sjukdom (HD) är ett neurodegenerativt tillstånd som orsakas av mutationer i huntingtin gen (Htt), och resulterar till upprepade glutamin (polyQ) i Htt-proteinet. Muterad Htt kan inte vika sig ordentligt och börjar därför aggregera i celler. READ MORE

  5. 4. Impact of the autoencoder-based FINTA tractogram filtering method on brain networks in subjects with Mild Cognitive Impairment

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Teodor Pstrusiński; [2023]
    Keywords : Tractography; Autoencoder; diffusion MRI; Filtering; Graph; Connectome; Traktografi; Autoencoder; diffusions MRT; Filtrering; Graf; Konnektom;

    Abstract : Diffusion Magnetic Resonance Imaging (dMRI) is a method for measuring molecular diffusion in biological tissue microstructure. This information can be used to predict the location and orientation of white matter fibers in the brain, a process known as tractography. READ MORE

  6. 5. Expression and purification of pyruvate transporting human mitochondrial pyruvate carrier (MPC) protein complex for structural studies

    University essay from Lunds universitet/Examensarbeten i molekylärbiologi

    Author : Markus Wendler; [2022]
    Keywords : Biology and Life Sciences;

    Abstract : Pyruvate is one of the main molecules needed for the citric acid cycle, which produces energy in the form of ATP. The citric acid cycle reaction occurs in the mitochondrial matrix, and for pyruvate to participate in the reaction, it needs to be transported from the cytosol across the mitochondrial membranes into the mitochondrial matrix. READ MORE