Essays about: "Neurodegenerative diseases"

Showing result 1 - 5 of 50 essays containing the words Neurodegenerative diseases.

  1. 1. Chromatin accessibility analysis of spaceflight mouse brains using ArchR

    University essay from KTH/Genteknologi

    Author : Raphaël Mauron; [2023]
    Keywords : Single nuclei ATAC-sequencing; Space Biology; DNA Chromatin accessibility; Neurodegenerative; ArchR; ATAC-sekvensering av enskilda kärnor; rymdbiologi; tillgänglighet av DNA kromatin ; neurodegenerativa sjukdomar; ArchR;

    Abstract : Mänsklig utforskning av månen och Mars innebär stora utmaningar för människans fysiologi och hälsa på grund av de unika miljöfaktorer som följer av långvariga rymduppdrag. Rymdbiologiska experiment har blivit ett viktigt verktyg för att studera effekterna som mikrogravitation och rymdstrålning har på levande organismer, i syfte att förstå och minska dessa utmaningar. READ MORE

  3. 2. Neuropsychiatric Symptoms in Alzheimer's Disease: Associations with Beta Amyloid and Potential New Cutoff Points on Neuropsychiatric Assessment Scales

    University essay from Lunds universitet/Institutionen för psykologi

    Author : David Christopher Wimmer; [2023]
    Keywords : Alzheimer s disease; dementia; neuropsychiatric symptoms; apathy; cognitively healthy; cognitively impaired; ROC analysis; Social Sciences;

    Abstract : Neuropsychiatric Symptoms (NPS) have been shown to be associated with Alzheimer's disease ( AD). They negatively affect disease outcome and could play a future role in the detection of prospective AD cases. READ MORE

  4. 3. Detection and quantification of post-translational modifications in non-invasive samples : Phosphoproteins as biomarkers and a market analysis of protein quantification technologies

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Sammi Baudin; Hillevi Fjellström; Aron Kraft; Erica Lamberg; Måns Rosenbaum; Hanna Sjöstrand; [2023]
    Keywords : Phorphorylation; Proteomics; Biomarkers; Phosphoproteins; PTM; Amyotrophic lateral sclerosis; ALS; Alzheimer s disease; Parkinson s disease; Cancer; xMAP; SIMOA; NULISA; PEA; ELISA; Mass spectrometry; SomaScan;

    Abstract : Post-translational modifications (PTMs) of proteins can be a sign and/or cause of disease. These modified proteins have the potential to be used as biomarkers for diagnostic purposes. However, research in the field is limited. READ MORE

  5. 4. Effect of DNAJB6 on α-synuclein amyloid fibril aggregation and dis-aggregation

    University essay from Lunds universitet/Biofysikalisk kemi

    Author : Josef Getachew; [2023]
    Keywords : α-synuclein; alpha-synuclein; chaperones; DNAJB6; the unhappy chaperone; parkinsons disease; biophysical chemistry; biochemistry; Biology and Life Sciences; Chemistry; Technology and Engineering;

    Abstract : Amyloid proteins are a group of proteins with the ability to form large fibrillar aggregates, identifiable by their cross-β core structure. These aggregates are linked to several different neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease and due to the growing rate of people diagnosed, there is a need to combat these diseases. READ MORE

  6. 5. Transcriptional basis of Huntington’s Disease: Gene expression analysis indicate increased immune responses in the brain and mitochondrial dysfunction in adipose tissues of HD model mouse

    University essay from KTH/Proteinvetenskap

    Author : Intisar Salim; [2023]
    Keywords : Huntington’s Disease; mRNA-seq; tissue specific gene expression; cerebrospinal fluid; biomarker; Huntingtons sjukdom; mRNA-seq; vävnadsspecifik genexpression; cerebrospinalvätska; biomarkör;

    Abstract : Huntingtons sjukdom (HD) är ett neurodegenerativt tillstånd som orsakas av mutationer i huntingtin gen (Htt), och resulterar till upprepade glutamin (polyQ) i Htt-proteinet. Muterad Htt kan inte vika sig ordentligt och börjar därför aggregera i celler. READ MORE