Essays about: "Non-coding RNA"

Showing result 1 - 5 of 22 essays containing the words Non-coding RNA.

  1. 1. Non-coding RNAs as therapeutic agents : The future of therapy

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Hederoth Gustaf; Lyngå Olivia; Rudqvist Olivia; Jeppsson Rebecka; Hogolof Saida; Svanberg Sara; Kauppinen Veera; [2022]
    Keywords : Non-coding RNA; Oligonucleotide therapeutics;

    Abstract : Non-coding RNA (ncRNA) therapeutics are based on short oligonucleotides, both naturally occurring and artificial, which target RNA in a site-specific way to modulate gene expression. As of today, 12 synthetically produced ncRNA-based drugs are available on the market in the US and Europe, and there is a possibility of more to be approved in the near future. READ MORE

  2. 2. Comprehensive Analysis of lncRNA and circRNA Mediated ceRNA network in Psoriasis

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Saima Imran; [2022]
    Keywords : ;

    Abstract : Evidence is accumulating that noncoding RNAs and circRNA are involved in psoriasis; however, the competing endogenous RNA (ceRNA) mediated regulatory mechanisms in psoriasis are rarely reported. The research study aimed to comprehensively investigate the differences in the expression levels of circular RNA (circRNA), long non-coding RNA (lncRNA), microRNA (miRNA/miR), and mRNA in psoriasis. READ MORE

  3. 3. Future diagnostic of Sepsis : Biomarker miRSeps-5 manual vs robotic extraction and optimization of miRNA detection by Two-Tailed RT-qPCR technology

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Erika Kasaras; [2022]
    Keywords : ;

    Abstract : Sepsis is a syndrome developed in response to infection when a body’s immune system cannot adequately respond to infection. To this day, sepsis holds a peak position in mortality rates worldwide. Currently, SOFA score and blood culturing as means to diagnose sepsis are standard. READ MORE

  4. 4. Extraction of miR-223 from human blood plasma and quantification using the two-tailed RT-qPCR and absolute quantification

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Lucija Marinkovic; [2021]
    Keywords : ;

    Abstract : Sepsis is a very dangerous and life-threatening disease that develops when the body’s reaction to infection causes damage to the body’s tissues and organs. It is difficult to diagnose it and it develops fast leading to a high mortality rate. READ MORE

  5. 5. Search for the Argonaute protein that governs miRNA regulation in Dictyostelium discoideum

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Miranda Åström; [2021]
    Keywords : Argonaute proteins; RNA interference; miRNA; 3xFLAG-tag;

    Abstract : MicroRNAs are small non-coding RNAs that regulate gene expression through RNA interference. These small RNAs enact gene silencing by forming a RNA-inducing silencing complex together with the effector protein Argonaute. The function of the Argonautes in the social amoeba Dictyostelium discoideum is not yet fully understood. READ MORE