Essays about: "ODN"

Found 3 essays containing the word ODN.

  1. 1. Early immune responses to an adjuvant (AbISCO-100) tested in porcine peripheral blood mononuclear cell

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Annika Bolind Bågenholm; [2009]
    Keywords : Adjuvant; porcine PBMC; ISCOM; ISCOMATRIX; AbISCO-100;

    Abstract : Immune stimulating complex (iscom) matrix is a formulation that is used as an adjuvant within research. The capability of the iscom matrix to elicit an immune response when not present together with an antigen has not been extensively investigated. READ MORE

  2. 2. Immunostimulatory DNA : studies on the importance of secondary structure formation and CpG-motifs for IFN-alpha induction/inhibition using ODNs related to the genome of porcine circovirus type 2

    University essay from SLU/Dept. of Molecular Biosciences

    Author : Josefine Elving; [2006]
    Keywords : interferon; porcine circovirus; PCV-2; CpG; secondary structure; inhibitory; PCR; ODN;

    Abstract : Nucleotide sequences containing CpG-motifs are recognized as immunomodulators in pigs among other species. Phosphodiester oligodeoxynucleotides (ODNs), such as ODN H, have been demonstrated to be potent inducers of interferon-alpha (INF-alpha) in porcine blood mononuclear cells (poPBMC) provided they are pre-treated with Lipofectin®. READ MORE

  3. 3. Interferon-α-modulatory sequences from the genome of porcine circovirus type 2

    University essay from SLU/Dept. of Molecular Biosciences

    Author : Frida Hasslung; [2003]
    Keywords : interferon; porcine circovirus; PCV-2; CpG; inhibitory;

    Abstract : Porcine circovirus (PCV) type 2 is an emerging pathogen among pigs, which has been associated with several severe disease syndromes. To date little is known of the pathogenesis and epidemiology of PCV, and how the virus affects the immune system of the host. READ MORE