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Found 2 essays matching the above criteria.

1. 1. The impact of various chromatographic conditions on the separation of modified and unmodified oligonucleotides

   University essay from Karlstads universitet

   Author : Lewis Frazer; [2021]
   Keywords : Oligonucleotide; Modified oligonucleotides; Ion-pair chromatography; Chromatography; Analytical chemistry; TEAA; DBA; Chemistry; Oligonukleotid; Modifierade oligonukleotider; Jonpars kromatografi; Kromatografi; Analytisk kemi; TEAA; DBA; Kemi;

   Abstract : In this study, the effects of certain chromatographic conditions on various modified and unmodified oligonucleotides were investigated. At the forefront of this study was the investigation of a new Ion-pair Reversed-phase liquid chromatography (IP-RPLC) method, that had the potential to replace a previously established triethylammonium acetate (TEAA) IP-RPLC method developed for oligonucleotide separations. READ MORE

3. 2. Functionalization and Evaluation of Nanoparticle Probes for the Development of a 14-Plex Diagnostic assay

   University essay from KTH/Kemi

   Author : Samuel Narmack; [2021]
   Keywords : Functionalization; multiplex; probing; diagnostics; nanoparticles; Funktionalisering; multiplexera; sonder; diagnostik; nanopartiklar;

   Abstract : Detta projekt var ett samarbete mellan Aplex Bio AB och Scilifelab. Projektets mål var att utveckla en molekylär diagnostisk panel med förmågan att detektera och diskriminera mellan 14 olika typer av patogener. Projektet innehåller 4 kapitel med fokus på olika mål. READ MORE