Essays about: "Optogenetics"

Found 5 essays containing the word Optogenetics.

  1. 1. Validation of micro-platelet LED for subcellular optogenetic activation in primary cell cultures

    University essay from Lunds universitet/Fasta tillståndets fysik; Lunds universitet/Fysiska institutionen

    Author : Daniel Jaghobi Pourshalmani; [2018]
    Keywords : Optogenetics; epilepsy; microplatelet; LED; primary cell cultures; adhesion proteins; electrophysiology; Medicine and Health Sciences;

    Abstract : Epilepsy is to this day still a serious neurological diseases where treatments such as pharmaceutical agents and surgery can at most alleviate the symptoms, but not cure it. This disease is still not fully understood at a cellular and network-level, but the recent advancements in the field of optogenetics can serve as an alternative way of studying the brain and diseases such as epilepsy. READ MORE

  2. 2. μLEDs for optogenetics

    University essay from Lunds universitet/Fasta tillståndets fysik; Lunds universitet/Fysiska institutionen

    Author : Lukas Wendt; [2018]
    Keywords : μLED; microLED; optogenetics; nitrides; platelets; LNL; epilepsy; Technology and Engineering;

    Abstract : Optogenetics is unfolding new ways for us to study the nervous system and could one day be a standard approach to treat neurological diseases like epilepsy. To selectively study the effects on a subcellular level, microscopic light sources are needed. READ MORE

  3. 3. Using Optogenetics and Fictive Locomotion to Investigate the Effects of Inhibiting Renshaw Cells on Normal Locomotion in P3 Mice

    University essay from Uppsala universitet/Institutionen för biologisk grundutbildning

    Author : Frida Niss; [2016]
    Keywords : Optogenetics; Fictive locomotion; Spinal cords; Renshaw cells; Ventral root recording;

    Abstract : The circuit of recurring inhibition between motor neurons and Renshaw cells in the spinal cord has been known for around 70 years, though no determined function has been outlined as of yet. Renshaw cells are thought to be part of the central pattern generator in the spinal cord establishing them as an important part of the animal’s locomotive properties. READ MORE

  4. 4. Characterization of the synaptic connectivity patterns of genetically defined neuron types in circuits that regulate dopamine and serotonin

    University essay from KTH/Skolan för teknik och hälsa (STH)

    Author : Alexandros Ikaros Pavlopoulos; [2014]
    Keywords : neuroscience; lateral habenula; optogenetics; neuronal populations; neurons; brain; dopamine; serotonin; dual viral system; retrograde viral tracing; globus pallidus; rabies virus; reward; basal ganglia;

    Abstract : The Lateral Habenula (LHb) have been implicated in both reward-seeking behavior and in depressive disorders due to its modulatory effects on dopamine rich areas. Excitatory projections from LHb target GABAergic interneurons of both ventral tegmental area (VTA) and rostromedial tegmental nucleus (RMTg) and consequently provide strong inhibition on VTA‟s dopaminergic neurons. READ MORE

  5. 5. Optogenetic Kindling

    University essay from Lunds universitet/Atomfysik; Lunds universitet/Matematisk fysik; Lunds universitet/Fysiska institutionen

    Author : Esbjörn Melin; [2013]
    Keywords : optogenetics; epilepsy; channelrhodopsin; isoflurane; ketamine; EEG; kindling; temporal lobe epilepsy; TLE; seizure; optrode; hippocampus; Thy1; Technology and Engineering; Medicine and Health Sciences;

    Abstract : Epilepsy is a common disease that affects about 1 % of the population. The neurological disease is characterised by episodes of neural hyperactivity (seizures) and neural synchronization that can have behavioural manifestations such as convulsions. READ MORE