Essays about: "PAR4"

Found 3 essays containing the word PAR4.

1. 1. Human platelet aggregation induced via protease-activated receptor 1 (PAR1)signaling is reversed by nitric oxide (NO) through inhibition of a Rho-kinase/ROCK-mediated pathway

   University essay from Institutionen för fysik, kemi och biologi

   Author : Patrik Björn; [2010]
   Keywords : Platelet; nitric oxide; PAR1; Rho-kinase; ROCK;

   Abstract : Human platelets are constantly regulated by activating and inhibitory effectors. Thrombin,the most potent platelet agonist, induces signaling through the protease-activated receptors(PARs) 1 and 4 which in turn convey their signal by coupling to G-proteins. READ MORE

3. 2. The role of PAR1 and PAR4 in platelet PAI-1 secretion

   University essay from Institutionen för fysik, kemi och biologi

   Author : Emma Löfgren; [2009]
   Keywords : ;

   Abstract : In Sweden about 26000 people are affected by myocardial infarction (MI) every year. Coronary vascular diseases and cerebrovascular diseases with blood flow disruption caused by thrombi are actually the most common cause of death. READ MORE

4. 3. Thrombin receptor signalling in platelets: PAR1, but not PAR4, is rapidly desensitized

   University essay from Institutionen för fysik, kemi och biologi

   Author : Linda Haglund; [2009]
   Keywords : Nitric oxide; PAR1; PAR4; platelets; receptor desensitization;

   Abstract : Platelets play a key role in primary haemostasis but are also related to the pathogenesis of arterial thrombosis. Thrombin is the most effective agonist inducing platelet activation. Human platelets express two G-protein coupled thrombin receptors (GPCRs), called protease activated receptor (PAR)1 and PAR4. READ MORE