Essays about: "PDAC"

Found 5 essays containing the word PDAC.

  1. 1. Impact of insulin, glucagon and the I-G complex on cell viability and metabolism in Panc-1

    University essay from Högskolan i Skövde/Institutionen för hälsovetenskaper

    Author : Katarina Brantingson Skogfält; [2021]
    Keywords : ;

    Abstract : Cancer has been found not only to be a disease of genetic mutations, but also a metabolic state by which insulin and glucagon has an impact on cancer cells. Pancreatic adenocarcinoma (PDAC) is a highly lethal cancer with high risk of recurrence of cancer cells after cancer therapy treatment with a worse outcome. READ MORE

  3. 2. Characterization of Iron Oxide Nanoparticle-Based Contrast Agent in Photoacoustic Imaging and Magnetic Resonance Imaging

    University essay from KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Author : Jimmy Zheng; [2021]
    Keywords : Photoacoustic imaging; magnetic resonance imaging; iron oxide nanoparticle; multimodal contrast agent;

    Abstract : Pancreatic ductal adenocarcinoma (PDAC) is one of the most difficult type of cancer to treat, due to late diagnosis which is a result of vague symptoms and lack of biomarkers, as well as refractory behavior toward current treatment protocols. Imaging of the disease progression therefore plays a crucial role in identifying potentially curable PDAC patients at an early stage. READ MORE

  4. 3. Investigating the cause of reduction of lactate production in Panc-1 cell lines when subjected to digitoxin

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Israel Tshibangu; [2021]
    Keywords : ;

    Abstract : Pancreatic ductal adenocarcinoma (PDAC) yet remains one of the top 10 most prevalent and top five most common cause of cancer-related deaths solely in the United States. Its metastatic deviation from most cancer types rends it one of the most subtle yet perturbating disease. READ MORE

  5. 4. Knockout studies of Panc1 cells

    University essay from KTH/Tillämpad fysik

    Author : Martin Sundin; [2021]
    Keywords : PDAC; crosstalk; stroma; spheroid; western blot; viability; gemcitabine.; PDAC;  verh rning; stroma; sf roid; western blot; viabilitet; gemcitabine.;

    Abstract : Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal form of cancerwith very few available treatment options of which none has great effect.Cancer cells and stromal cells such as stellate cells which exist in abundancein PDAC interact by crosstalk, resulting in a tumorigenic collective response. READ MORE

  6. 5. Utilization of cancer-specific genome-scale metabolic models in pancreatic ductal adenocarcinomas for biomarkers discovery and patient stratification

    University essay from Högskolan i Skövde/Institutionen för biovetenskap

    Author : Mohamed Al Shobky; [2019]
    Keywords : Genome-Scale Metabolic Models; GEM; Pancreatic Ductal Adenocarcinomas; pancreatic cancer; cancer metabolism; biomarker; LDHA; L-lactate dehydrogenase A chain;

    Abstract : Pancreatic Ductal Adenocarcinomas initiates in the exocrine part of the pancreatic tissue and represents over 90% of all the pancreatic cancers. Pancreatic Ductal Adenocarcinomas are extremely aggressive and are one of the most lethal malignant neoplasms. The five-year relative survival is currently less than 8% of the patients. READ MORE