Essays about: "PK"

Showing result 16 - 20 of 37 essays containing the word PK.

  1. 16. Linking Systems Models of Pharmacology with Behavioural Models of Adherence : A Feasibility Study

    University essay from KTH/Medicinteknik och hälsosystem

    Author : Simon Jenner; Dennis Amphan; [2020]
    Keywords : Pharmacology; Pharmacokinetics; Pharmacodynamics; PKPD-model; Diabetes; Adherence; Modelling; Feasibility; Farmakologi; Farmakokinetic; Farmakodynamik; PKPD-model; Diabetes; ̊Atlydnad; Modellering; Genomf ̈orbarhet;

    Abstract : Pharmacokinetic (PK)- and pharmacodynamic (PD) modeling are useful tools whenassessing treatment effect. A patient’s adherence can potentially be rate-limiting, since it isthe first process in a chain of processes that determines treatment effect. READ MORE

  3. 17. Case Study: Digitization of a User Interface : Investigating the use of a touch screen in Helicopter 14

    University essay from KTH/Maskinkonstruktion (Inst.)

    Author : Hanna Abrahamsson; Linn Karlsson; [2020]
    Keywords : ;

    Abstract : A user interface should be intuitive to allow efficient and safe execution of tasks. Helicopter 14 (HKP 14) has operator consoles with an analog user interface, called Programmable Keys (PK), to control a Mission Management System (MMS). The idea of replacing the PK with touch technology has arisen. READ MORE

  4. 18. An Investigation of Semantic Interoperability with EHR systems for Precision Dosing

    University essay from KTH/Medicinteknik och hälsosystem

    Author : Jovia Namugerwa Mukwaya; [2020]
    Keywords : precision dosing; ontology; semantic interoperability; precision medicine;

    Abstract : In healthcare, vulnerable populations that are using medications with a narrow therapeutic index and wide interpatient PK/PD (pharmacokinetic/pharmacodynamic modelling) variability are increasing. As such, variable dosage regimens may result in severe therapeutic failures or adverse drug reactions (ADR). READ MORE

  5. 19. Atropins farmakologi, tarmens respons och kolik hos häst plasmakoncentrationen : Plasmakoncentrationen atropin och biomarkörer för tarmmotilitet

    University essay from SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Author : Anna Sundell; [2020]
    Keywords : Atropin; PK PD-modell; ; uveit; EIG; Kklik;

    Abstract : Inflammation i ögats uvea, så kallad uveit, är en smärtsam och vanlig komplikation till olika sjukdomstillstånd i hästars ögon. Vid uveit uppstår en spasm i pupillen och i ciliarkroppen vilket är smärtsamt och komplikationer i form av sammanväxningar (så kallade synechier) mellan lins och iris kan leda till kvarstående synnedsättning eller blindhet. READ MORE

  6. 20. Models for predicting efflux transport over the blood-brain barrier

    University essay from Uppsala universitet/Institutionen för farmaci

    Author : Marjaneh Janani; [2020]
    Keywords : efflux transport; brain; blood-brain-barrier; Verapamil; Risperidone; Prazosin;

    Abstract : Aim: The general aim of this research is development and evaluation of novel methods for predicting active transport over the human blood-brain-barrier (BBB), while this project specifically aims to i) review the literature and select suitable methods and substrates, ii) develop models for determining in vitro kinetic properties of selected compounds, analyze the in vitro data using the developed models and to use Maximum Transport Activity (MTA) approach (Karlgren et al., 2012), iii) perform Physiology Based Pharmacokinetic (PBPK) modelling and compare to in vivo literature data. READ MORE