Essays about: "PacBio"
Found 3 essays containing the word PacBio.
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1. Whole-Genome Sequencing of two Swedish Individuals on PromethION
University essay from Lunds universitet/Examensarbeten i bioinformatikAbstract : Background: Chromosomes can undergo various changes such as deletions, inversions, insertions, and/or translocations resulting in structural variation differences between individuals. Structural variants are a common source of variability in the human genome and have been known to be associated with common diseases such as autism, cancer, and rare human diseases [1, 2]. READ MORE
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2. Validation of a new software for detection of resistance associated substitutions in Hepatitis C-virus
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Hepatitis C infection is a global disease that causes an estimated 399,000 deaths per year. Treatment has improved dramatically in recent years through the development of direct acting antivirals that target specific regions of the Hepatitis C virus (HCV). READ MORE
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3. Evaluation of de novo assembly using PacBio long reads
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : New sequencing technologies show promise for the construction of complete and accurate genome sequences, by a process called de novo assembly that joins reads by overlap to longer contiguous sequences without the need for a reference genome. High-quality de novo assembly leads to better understanding in genetic variations. READ MORE