Essays about: "PhoP"
Found 1 essay containing the word PhoP.
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1. Searching for novel protein-protein specificities using a combined approach of sequence co-evolution and local structural equilibration
University essay from Uppsala universitet/Institutionen för biologisk grundutbildningAbstract : Greater understanding of how we can use protein simulations and statistical characteristics of biomolecular interfaces as proxies for biological function will make manifest major advances in protein engineering. Here we show how to use calculated change in binding affinity and coevolutionary scores to predict the functional effect of mutations in the interface between a Histidine Kinase and a Response Regulator. READ MORE
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